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  3. Nafenodone

Nafenodone 是一种抗抑郁剂。Nafenodone 可以降低收缩的频率和幅度,并延长窦房结恢复时间。Nafenodone 在离体大鼠血管平滑肌中,可以抑制门静脉节段的自发机械活动,其 IC50 值为1.4 μM。Nafenodone 还能松弛由高浓度 K+ 和去甲肾上腺素引起的收缩。

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Nafenodone

Nafenodone Chemical Structure

CAS No. : 92615-20-8

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  • 生物活性

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生物活性

Nafenodone is an antidepressant agent. Nafenodone can reduce the rate and amplitude of contractions and lengthen sinus node recovery time. Nafenodone can inhibit the spontaneous mechanical activity in portal vein segmens with an IC50 of 1.4 μM in rat isolated vascular smooth muscle. Nafenodone relaxes the contractions induced by high K+ and noradrenaline[1][2].

分子量

293.40

Formula

C20H23NO

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Nafenodone
目录号:
HY-165387
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