2. Immunology/Inflammation
  3. CD19
  4. NKX019

NKX019 是一种靶向 CD19 的 CAR-NK 细胞产品，包含 CD3 zeta 和 OX40 共刺激结构域，以及一个用于激活的独立膜结合型 IL-15；该产品为冷冻保存的同种异体产品，来源于健康供体的 NK 细胞。NKX019 可用于复发/难治性 B 细胞恶性肿瘤的研究。

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NKX019

NKX019 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户。

规格 是否有货
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Customer Review

NKX019 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NKX019 is an allogeneic, cryopreserved CAR-NK cell product targeting CD19, equipped with CD3ζ and OX40 co-stimulatory domains, and an independent membrane-bound IL-15 for activation. It is derived from natural killer (NK) cells of healthy donors and is being investigated for the treatment of relapsed/refractory B-cell malignancies[1].

反应种属

Human
IC50 & Target

CD19
基因 ID

930  [NCBI]

Accession
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NKX019 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NKX019NKX 019NKX-019CD19phase I clinical trialNHL patientsrelapsed/refractoryIL-15b-cell malignanciesCAR-NK cellOX40CD3 zetahealthy donor NK cellsInhibitorinhibitorinhibit

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产品名称：
NKX019
目录号：
HY-P991901
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