2. Cytoskeleton Protein Tyrosine Kinase/RTK
  3. Integrin VEGFR
  4. NYLTHRQ

NYLTHRQ 是一种肽。NYLTHRQ 可特异性阻断 sVEGFR1-i13 与 β1 整合素之间的相互作用并抑制 VEGFR1 和 VEGFR2 的激活。NYLTHRQ 可抑制癌细胞增殖。NYLTHRQ 可用于肺鳞状细胞癌等肿瘤的研究。

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Custom Peptide Synthesis

NYLTHRQ

NYLTHRQ Chemical Structure

CAS No. : 1004284-41-6

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NYLTHRQ 相关抗体

Top Publications Citing Use of Products

查看 Integrin 亚型特异性产品:

查看所有亚型
αvβ1 αvβ3 αvβ5 αvβ6 αvβ8 α5β1 α1β1 α2β1 α4β1 α9β1 αIIbβ3 α4β7 αLβ2

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VEGFR1/Flt-1 VEGFR2/KDR/Flk-1 VEGFR3/Flt-4

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

NYLTHRQ is a peptide. NYLTHRQ specifically blocks the interaction between sVEGFR1-i13 and β1 integrin, and inhibits the activation of VEGFR1 and VEGFR2. NYLTHRQ inhibits cancer cell proliferation. NYLTHRQ can be used in the research of tumors such as lung squamous cell carcinoma[1].

IC50 & Target[1]

VEGFR1

 

VEGFR2

 

体外研究
(In Vitro)

NYLTHRQ (10 μg/mL；72 h) 在 MGH7 细胞中可特异性阻断 sVEGFR1-i13 与 β1 整合素的相互作用，抑制 VEGFR 的激活，并降低细胞的增殖活性[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

NYLTHRQ 相关抗体:

Cell Proliferation Assay[1]

Cell Line: MGH7 squamous cell lung carcinoma (SQLC) cells
Concentration: 10 μg/ml
Incubation Time: 72 h
Result: Prevented the activation of VEGFR1 (Tyr1213) and VEGFR2 (Tyr1214) proteins.
Blocked the increased cell proliferation induced by sVEGFR1-i13-containing conditioned supernatants.
分子量

931.01

Formula

C40H62N14O12
CAS 号
Sequence

Asn-Tyr-Leu-Thr-His-Arg-Gln
Sequence Shortening

NYLTHRQ
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

NYLTHRQ 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NYLTHRQ1004284-41-6IntegrinVEGFRVascular endothelial growth factor receptorVEGFR1lung squamous cell carcinoma cellsMGH7 SQLC cellsβ1 integrinVEGFR2squamous cell lung carcinomasVEGFR1-i13Inhibitorinhibitorinhibit

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产品名称：
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目录号：
HY-P11649
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