2. Apoptosis Immunology/Inflammation
  3. TNF Receptor Interleukin Related NO Synthase
  4. Oleracone

Oleracone 是一种可从马齿苋 (Portulaca oleracea L.) 发现的生物碱。Oleracone 在 LPS (HY-D1056) 诱导的 RAW 264.7 巨噬细胞模型中表现出显著抗炎作用，可抑制 NO 生成，并显著抑制促炎细胞因子 TNF-α、IL-6 和前列腺素 E₂ (PGE₂) 的分泌。Oleracone 可用于研究炎症疾病。

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Oleracone

Oleracone Chemical Structure

CAS No. : 1863920-09-5

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Oleracone 相关抗体

Top Publications Citing Use of Products

查看 TNF Receptor 亚型特异性产品:

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TNFRSF1A/CD120a TNFRSF3/CD18 TNFRSF4 TNFRSF5/CD40 TNFRSF6/Fas/CD95 TNFRSF7/CD27 TNFRSF8/CD30 TNFRSF9/4-1BB/CD137 TNFRSF12A/TWEAK TNFRSF16/NGF Receptor/CD271 TNFRSF18/GITR/CD357

查看 Interleukin Related 亚型特异性产品:

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IL-1 IL-2 IL-3 IL-4 IL-5 IL-6 IL-8 IL-10 IL-12 IL-13 IL-15 IL-17 IL-23 IL-7 IL-33 IL-22 IL-18

查看 NO Synthase 亚型特异性产品:

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nNOS iNOS eNOS

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Oleracone is a type of alkaloid that can be found in Portulaca oleracea L.. Oleracone exhibits a significant anti-inflammatory effect in the RAW 264.7 macrophage model induced by LPS (HY-D1056), capable of inhibiting NO production and significantly suppressing the secretion of pro-inflammatory cytokines TNF-α, IL-6, and prostaglandin E₂ (PGE₂). Oleracone can be used for the study of inflammatory diseases[1].

分子量

231.29

Formula

C14H17NO2
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Oleracone 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Oleracone1863920-09-5TNF ReceptorInterleukin RelatedNO SynthaseTumor Necrosis Factor ReceptorTNFRILNitric oxide synthasesNOSanti-inflammationoleraconepharmacokineticsrat plasmaultra high-performance liquid chromatographyInhibitorinhibitorinhibit

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目录号：
HY-N17239
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