2. GPCR/G Protein
  3. Endothelin Receptor
  4. Patecibart

Patecibart  (Synonyms: Getagozumab; GMA-301)

目录号: HY-P990089
技术支持

Patecibart 是一种人源化免疫球蛋白 G4-kappa、抗 EDNRA 单克隆抗体。Patecibart 是一种内皮素受体拮抗剂。

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CAS No. : 2642374-04-5

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     可免费申领三个不同产品的试用装。

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规格 是否有货
1 mg   询价  
5 mg   询价  
10 mg   询价  

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Patecibart 相关抗体

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ETA ETB

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Patecibart is a humanized immunoglobulin G4-kappa, anti-EDNRA monoclonal antibody. Patecibart is an endothelin receptor antagonist[1].

同型

Human IgG4 kappa
推荐同型对照抗体
反应种属

Human
IC50 & Target

EDNRA
Clinical Trial
基因 ID

1909  [NCBI]

Accession
应用

ELISA, FACS, Functional assay
偶联物

Unconjugated
复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.
CAS 号
性状

液体

颜色

Colorless to light yellow

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
Format
  • Human IgG4 kappa
Biological Activity
  • Flow cytometry analysis of Raji cells with HY-P990089 at 20nM (Red). 20ng/mL of FcγRI (CD64), FcγRII (CD32), and FcγRIII (CD16) were added to block the binding of Fc of antibody to cells respectively. Goat anti human IgG Fc(Alexa Fluor488) was used as the secondary antibody at 1/400 dilution. Unlabeled control - Unlabelled cells (Gray).
纯度 & 产品资料
参考文献

Patecibart 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Patecibart2642374-04-5Getagozumab GMA-301GMA301GMA 301GMA-301Endothelin ReceptorG4-kappaEDNRAendothelin receptorInhibitorinhibitorinhibit

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目录号：
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