2. Antibody-drug Conjugate/ADC Related JAK/STAT Signaling Protein Tyrosine Kinase/RTK Immunology/Inflammation
  3. Antibody-Drug Conjugates (ADCs) EGFR Toll-like Receptor (TLR)
  4. Pertuzumab zuvotolimod

Pertuzumab zuvotolimod  (Synonyms: SBT6050)

目录号: HY-P9994
技术支持

Pertuzumab zuvotolimod (SBT6050) 是一种抗 HER2 抗体-药物偶联物 (ADC)。Pertuzumab zuvotolimod 由人源化抗 HER2 抗体 (Pertuzumab) (HY-P9912A)、连接体、TLR8 激动剂有效载荷组成，且 ADC 的药物-连接体偶联物为 Zuvotolimod (HY-145620)。Pertuzumab zuvotolimod 通过直接激活髓系细胞并随后诱导 T 细胞和 NK 细胞溶细胞活性，有效诱导多种抗肿瘤免疫活性。Pertuzumab zuvotolimod 可用于HER2 表达实体瘤研究。

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CAS No. : 2500674-05-3

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Pertuzumab zuvotolimod 相关抗体

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生物活性

Pertuzumab zuvotolimod (SBT6050) is an anti-HER2 antibody-drug conjugate (ADC). Pertuzumab zuvotolimod is composed of a humanized anti-HER2 antibody (Pertuzumab) (HY-P9912A), a linker, a TLR8 agonist payload, and the drug-linker conjugate for ADC is Zuvotolimod (HY-145620). Pertuzumab zuvotolimod potently induces multiple anti-tumor immune activities through the direct activation myeloid cells and the subsequent induction of T and NK cell cytolytic activity. Pertuzumab zuvotolimod can be used for HER2-expressing solid tumors research[1].

IC50 & Target

ERBB2/HER2/CD340
CAS 号
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Format
  • Human IgG1 kappa
纯度 & 产品资料
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Pertuzumab zuvotolimod 相关分类

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Keywords:

Pertuzumab zuvotolimod2500674-05-3SBT6050SBT 6050SBT-6050Antibody-Drug Conjugates (ADCs)EGFRToll-like Receptor (TLR)Antibody-Drug ConjugatesEpidermal growth factor receptorErbB-1HER1HER2Antibody-drug conjugateADCAnti-tumorImmuneSolid tumorsInhibitorinhibitorinhibit

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