2. Cytoskeleton
  3. Clathrin
  4. Pitstop 2d

Pitstop 2d 是一种 Clathrin 抑制剂，其 IC50 为 <2 μM。Pitstop 2d 与 Clathrin N 端 β 螺旋桨结构域结合，抑制 Clathrin 的功能和动力学，并阻碍 VSV 的进入。Pitstop 2d 抑制网格蛋白介导的内吞 (Endocytosis) 作用。Pitstop 2d 不抑制非网格蛋白依赖性内吞作用。

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Pitstop 2d

Pitstop 2d Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构（单位）同一产品试用装仅限申领一次，同一机构（单位）一年内

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Pitstop 2d 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pitstop 2d is a Clathrin inhibitor with an IC50 of <2 μM. Pitstop 2d binds to Clathrin N-terminal β-propeller domain, inhibits Clathrin function and dynamics and impairs VSV entry. Pitstop 2d inhibits Clathrin-mediated Endocytosis. Pitstop 2d does not inhibit clathrin-independent Endocytosis[1].

IC50 & Target

IC50: <2 μM (Clathrin TD)[1]
分子量

486.56

Formula

C26H18N2O4S2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Pitstop 2d 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Pitstop 2dClathrinInhibitorinhibitorinhibit

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目录号：
HY-186018
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