1. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  2. Interleukin Related Reactive Oxygen Species (ROS)
  3. PNA5

PNA5 是一种新型的、可透过血脑屏障的糖基化 angiotensin-(1-7) 肽和 MasR 激动剂。PNA5 可抑制 IL-7,增加 IL-10。PNA5 可抑制 ROS 生成,降低 Iba-1 表达。PNA5 具有持续的认知保护作用。PNA5 可恢复受损的脑功能性充血。PNA5 可用于炎症相关脑疾病的研究。

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Custom Peptide Synthesis

PNA5

PNA5 Chemical Structure

CAS No. : 2186644-51-7

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

PNA5 is a novel, blood-brain barrier permeable glycosylated angiotensin-(1-7) peptide and MasR agonist. PNA5 inhibits IL-7, increases IL-10. PNA5 inhibits ROS generation, decreases Iba-1 expression. PNA5 exhibits sustained cognitive protective effects. PNA5 rescues blunted cerebral functional hyperemia. PNA5 can be used in the research of inflammation-related brain diseases[1].

IC50 & Target[1]

IL7R

 

IL-10

 

分子量

1050.12

Formula

C45H71N13O16

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
PNA5
目录号:
HY-167153
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