1. 天然产物
  2. 植物 萜类
  3. 薯蓣科 三萜
  4. 粉背薯蓣
  5. Protoneodioscin

Protoneodioscin  (Synonyms: 原新薯蓣皂苷; NSC-698789)

目录号: HY-N17753
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Protoneodioscin 是一种呋甾烷醇皂苷,存在于粉背薯蓣 (Dioscorea collettii var. hypoglauca) 的根茎中。Protoneodioscin 对白血病等多种癌细胞具有选择性活性,但对结肠癌和肾癌细胞无活性。Protoneodioscin 可用于白血病等癌症研究。

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Protoneodioscin

Protoneodioscin Chemical Structure

CAS No. : 60478-69-5

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Protoneodioscin is a furostanol saponin found in the rhizomes of Dioscorea collettii var. hypoglauca. It exhibits selective activity against various cancer cell lines, including leukemia, but shows no activity against colon and renal cancer cells. Protoneodioscin can be used in research on cancers such as leukemia[1].

体外研究
(In Vitro)

Protoneodioscin (0.01-100 μM; 72 h) 对 60 种受试人类癌细胞系中的大多数具有细胞毒性,其中敏感性最高的为 K-562 白血病细胞 (GI50 = 0.49 μM),而白血病、中枢神经系统癌症和前列腺癌细胞亚组整体敏感性最高[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1049.20

Formula

C51H84O22

CAS 号
中文名称

原新薯蓣皂苷

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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