1. 天然产物
  2. 植物 黄酮类
  3. 豆科 黄酮
  4. 囊果紫檀
  5. Pseudobaptigenin

Pseudobaptigenin 是一种黄酮类化合物。Pseudobaptigenin 显示出非常好的抗白内障活性。Pseudobaptigenin 对抑制γ -晶体蛋白糖基化具有良好的结合亲和力。Pseudobaptigenin 还具有良好的 ADMET (吸收、分布、代谢、排泄和毒性)特性。

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Pseudobaptigenin

Pseudobaptigenin Chemical Structure

CAS No. : 90-29-9

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5 mg ¥788
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10 mg ¥1261
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25 mg ¥2519
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50 mg ¥4281
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Pseudobaptigenin is a flavonoid. Pseudobaptigenin shows very good anticataract activity. Pseudobaptigenin has good binding affinity for the inhibition of glycation against γ-crystallin protein. Pseudobaptigenin also has good ADMET (Absorption, Distribution, Metabolism, Excretion and Toxicity) property[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
BV-2 IC50
> 100 μM
Compound: 20
Anti-neuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
Anti-neuroinflammatory activity against mouse BV2 cells assessed as inhibition of LPS-induced nitric oxide production after 24 hrs by Griess assay
[PMID: 25466192]
C2C12 IC50
12.08 μg/mL
Compound: 7
Cytotoxicity against mouse C2C12 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against mouse C2C12 cells assessed as reduction in cell viability by MTT assay
[PMID: 33412152]
HEK293 EC50
22.34 μM
Compound: 7
Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
Agonist activity at human PPARdelta expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
[PMID: 23265844]
HEK293 EC50
26.94 μM
Compound: 7
Agonist activity at human PPARgamma expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
Agonist activity at human PPARgamma expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
[PMID: 23265844]
HEK293 EC50
8.9 μM
Compound: 7
Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
Agonist activity at human PPARalpha expressed in HEK293 cells cotransfected with PPREx4-TK-luc assessed as activation of luciferase activity measured after 48 hrs by transactivation assay
[PMID: 23265844]
MCF7 IC50
> 100 μM
Compound: 30a
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS/PMS assay
Antiproliferative activity against human MCF7 cells after 72 hrs by MTS/PMS assay
[PMID: 19932969]
SK-BR-3 IC50
> 100 μM
Compound: 30a
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTS/PMS assay
Antiproliferative activity against human SKBR3 cells after 72 hrs by MTS/PMS assay
[PMID: 19932969]
分子量

282.25

Formula

C16H10O5

CAS 号
性状

固体

颜色

Off-white to light brown

结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
溶解性数据
细胞实验: 

DMSO 中的溶解度 : 37.5 mg/mL (132.86 mM; 超声助溶; 吸湿的 DMSO 对产品的溶解度有显著影响,请使用新开封的 DMSO)

配制储备液
浓度 溶剂体积 质量 1 mg 5 mg 10 mg
1 mM 3.5430 mL 17.7148 mL 35.4296 mL
5 mM 0.7086 mL 3.5430 mL 7.0859 mL
查看完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息:

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

由于实验过程有损耗,建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
纯度 & 产品资料
参考文献

完整储备液配制表

* 请根据产品在不同溶剂中的溶解度选择合适的溶剂配制储备液;一旦配成溶液,请分装保存,避免反复冻融造成的产品失效
储备液的保存方式和期限:-80°C, 6 months; -20°C, 1 month。-80°C储存时,请在6个月内使用,-20°C储存时,请在1个月内使用。

可选溶剂 浓度 溶剂体积 质量 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.5430 mL 17.7148 mL 35.4296 mL 88.5740 mL
5 mM 0.7086 mL 3.5430 mL 7.0859 mL 17.7148 mL
10 mM 0.3543 mL 1.7715 mL 3.5430 mL 8.8574 mL
15 mM 0.2362 mL 1.1810 mL 2.3620 mL 5.9049 mL
20 mM 0.1771 mL 0.8857 mL 1.7715 mL 4.4287 mL
25 mM 0.1417 mL 0.7086 mL 1.4172 mL 3.5430 mL
30 mM 0.1181 mL 0.5905 mL 1.1810 mL 2.9525 mL
40 mM 0.0886 mL 0.4429 mL 0.8857 mL 2.2143 mL
50 mM 0.0709 mL 0.3543 mL 0.7086 mL 1.7715 mL
60 mM 0.0590 mL 0.2952 mL 0.5905 mL 1.4762 mL
80 mM 0.0443 mL 0.2214 mL 0.4429 mL 1.1072 mL
100 mM 0.0354 mL 0.1771 mL 0.3543 mL 0.8857 mL
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
Pseudobaptigenin
目录号:
HY-N10616
需求量:
{$root.selectProvice('甘肃省')}">甘肃省
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