1. Anti-infection
  2. Beta-lactamase Bacterial
  3. rel-Avibactam sodium

rel-Avibactam sodium  (Synonyms: NXL-104 sodium)

目录号: HY-14879E
产品使用指南 技术支持

rel-Avibactam (NXL-104) sodium 是一种 β-内酰胺酶 (β-lactamase) 抑制剂,具有广谱抗菌活性。rel-Avibactam sodium 在与 Ceftazidime (HY-B0593) 的组合中,对产生 Ambler A 类和 C 类 β-内酰胺酶的肠杆菌科细菌表现出显著的抑制效果。rel-Avibactam sodium 的 IC50 值远低于常用的 β-内酰胺酶抑制剂 Clavulanic acid (HY-A0256) 和 Ticarcillin (HY-139805),显示出其在抑制 TEM-1 和 P99 酶方面的高效性。

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rel-Avibactam sodium

rel-Avibactam sodium Chemical Structure

CAS No. : 1383814-68-3

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  • 参考文献

生物活性

Ent-Avibactam (NXL-104) sodium is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Cefazidime (HY-B0593), rel-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae bacteria that produce Ambler A and C types of β-lactamases. The IC50 value of rel-Avibactam sodium is much lower than that of commonly used β-lactamase inhibitors Clavulanic acid (HY-A0256) and Ticarcillin (HY-139805), demonstrating its high efficiency in inhibiting TEM-1 and P99 enzymes[1][2].

分子量

287.23

Formula

C7H10N3NaO6S

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献

rel-Avibactam sodium 相关分类

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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rel-Avibactam sodium
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HY-14879E
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