2. Metabolic Enzyme/Protease
  3. Factor Xa
  4. RPR 130737

RPR 130737 是一种选择性、强效且具有竞争性的 Xa 因子抑制剂，其 Ki 为 2.4 nM。RPR 130737 对凝血酶、活化蛋白 C、纤溶酶、组织型纤溶酶原激活剂和胰蛋白酶的选择性超过 1000 倍。RPR 130737 能够延长血浆活化部分凝血活酶时间和凝血酶原时间。RPR 130737 对血小板聚集无影响。RPR 130737 可用于心血管疾病的研究，如血栓。

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RPR 130737

RPR 130737 Chemical Structure

CAS No. : 205054-36-0

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RPR 130737 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

RPR 130737 is a selective, potent and competitive inhibitor for factor Xa with a Ki of 2.4 nM. RPR 130737 shows selectivity of more than 1000-fold over thrombin, activated protein C, plasmin, tissue-plasminogen activator and trypsin. RPR 130737 can prolong plasma activated partial thromboplastin time and prothrombin time. RPR 130737 shows no effect on platelet aggregation. RPR 130737 can be used for the research of cardiovascular disease, such as thrombosis[1].

分子量

471.55

Formula

C21H21N5O4S2
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

RPR 130737 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

RPR 130737205054-36-0RPR130737RPR-130737Factor XaFxafactor Xathrombinactivated protein Cplasmintissue-plasminogen activatortrypsinthromboplastin timeprothrombin timeplatelet aggregationthrombosisInhibitorinhibitorinhibit

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产品名称：
RPR 130737
目录号：
HY-106404
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