1. GPCR/G Protein
  2. Guanylate Cyclase
  3. S-3448

S-3448 是一种 Ataciguat (HY-17500) 衍生物。S-3448 是一种可溶性鸟苷酸环化酶 (sGC) 激动剂。S-3448 可激活含血红素和不含血红素的 sGC,且不依赖于 NO 和血红素。S-3448 可用于动脉高血压和肺动脉高压等心血管疾病的研究。

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S-3448

S-3448 Chemical Structure

CAS No. : 254877-04-8

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

S-3448 is a derivative of Ataciguat (HY-17500). S-3448 is a Soluble guanylate cyclase (sGC) agonist. S-3448 activates both the haem-containing and the haem-deficient form of sGC without depending on NO and heme. S-3448 can be used for cardiovascular diseases such as arterial hypertension and pulmonary hypertension research[1].

分子量

612.14

Formula

C25H26ClN3O7S3

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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  • 稀释计算器

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

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浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
S-3448
目录号:
HY-124074
需求量: