2. Metabolic Enzyme/Protease
  3. TMPRSS6
  4. Sapablursen sodium

Sapablursen sodium  (Synonyms: IONIS-TMPRSS6-Lrx sodium; ISIS 702843 sodium)

目录号: HY-177662A
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寡核苷酸使用指南 技术支持

Sapablursen sodium 是一种反义寡核苷酸，可减少 TMPRSS6 的生成，从而提高血清铁调素的表达量。血清铁调素是铁稳态的关键调节因子。Sapablursen 可用于如真性红细胞增多症等血液疾病的研究中。

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DNA, d([2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]m5rU-[2'-O-(2-methoxyethyl)]rA-T-sp-T-sp-m5C-sp-m5C-sp-A-sp-A-sp-A-sp-G-sp-G-sp-G-sp-[2'-O-(2-methoxyethyl)]m5rC-[2'-O-(2-methoxyethyl)]rA-[2'-O-(2-methoxyethyl)]rG-sp-[2'-O-(2-methoxyethyl)]m5rC-sp-[2'-O-(2-methoxyethyl)]m5rU), 5'-[26-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]-14,14-bis[[3-[[6-[[2-(acetylamino)-2-deoxy-β-D-galactopyranosyl]oxy]hexyl]amino]-3-oxopropoxy]methyl]-8,12,19-trioxo-16-oxa-7,13,20-triazahexacos-1-yl hydrogen phosphate], sodium salt (1:20)

Sapablursen sodium Chemical Structure

CAS No. : 2273008-00-5

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Sapablursen sodium 的其他形式现货产品:

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Sapablursen sodium 相关抗体

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Sapablursen sodium, an antisense oligonucleotide, is designed to reduce the production of TMPRSS6 resulting in increased expression of hepcidin, which is the key regulator of iron homeostasis. Sapablursen sodium can be used in the research of blood diseas

分子量

9071.01

Formula

C296H416N80Na20O155P20S13
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Sapablursen sodium 相关分类

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  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Sapablursen2273008-00-5IONIS-TMPRSS6-LrxISIS 702843ISIS702843ISIS-702843TMPRSS6Matriptase-2Transmembrane protease serine 6Inhibitorinhibitorinhibit

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