1. 一站式药筛
  2. 化合物库
  3. 类药多样性化合物库系列
  4. 特色多样性化合物库
  5. 10K Golden骨架库
10K Golden骨架库 - 10K Golden Scaffold Library

Cat. No.: HY-L927

一键复制产品信息

该化合物库采用骨架导向设计策略,每个独特的Bemis Murcko含有2个精心设计的衍生物分子,既保证了化学空间广泛覆盖(骨架多样性),也兼顾了在骨架结构基础上丰富官能团结构,为每个化学骨架提供初步的结构-活性关系探索能力,为后续的快速优化奠定基础,是高效药物发现的有用工具。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
- +

Compound Screening Libraries

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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情

活性描述 & 特点

Biological Activity

•    A unique collection of 10,000 compounds with 5,000 Bemis-Murcko scaffolds, making it a valuable tool for accelerating drug discovery.

•    Scaffold Diversity: The library contains a wide array of distinct chemical scaffolds, ensuring broad coverage of chemical space and maximizing the probability of identifying hit molecules.

•    Functional Group Richness: For each scaffold, two derivative molecules are designed, introducing functional groups with varying properties, sizes, and polarities at different sites to enable preliminary exploration of structure-activity relationships.

•    All compounds are available off the shelf.

•    All compounds are validated by LCMS or NMR to ensure high purity and quality.

产品详情

Product Details

Formulation:

A 10k compound library, which balances both excellent diversity and the capacity for preliminary analysis of structure-activity relationships, making it an ideal starting library for high-throughput screening.

Container:

96- or 384-well Plates with Peelable Foil Seals; 96-well Format Sample Storage Tubes with Screw Caps and Optional 2D Barcodes.

Storage:

-80°C

Shipping:

Blue ice or dry ice

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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称:
    10K Golden Scaffold Library
    目录号:
    HY-L927
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