2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 疾病相关化合物库
  6. 抗衰老化合物库 Mini
抗衰老化合物库 Mini - Anti-Aging Compound Library Mini

Cat. No.: HY-L034M

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研究表明，靶向衰老通路的药物在阿尔茨海默病、心血管疾病、代谢综合征、骨关节炎及多种恶性肿瘤等年龄相关疾病模型中展现出改善潜力，提示通过干预衰老生物学进程可能实现对多种慢性疾病的协同防治。在细胞衰老、端粒损耗、表观遗传失调和慢性炎症等核心衰老机制被逐步揭示的背景下，抗衰老研究已从传统表型干预转向靶向生物学年龄的关键通路调控。

MCE 抗衰老化合物库 Mini 正是基于这一前沿理念构建，聚焦于经遗传学或功能研究验证的衰老相关靶点，共计 381 个化合物旨在为衰老生物学及干预策略开发提供系统性研究工具。化合物库涵盖 mTOR、SIRT、能量代谢、细胞衰老清除、线粒体功能优化及端粒维持等核心机制，每个靶点精选 1-5 个活性明确、具有代表性的化合物，覆盖从临床前工具分子到临床在研药物的完整转化谱系。

我们将在明确您的产品用途后，向符合资质的客户通过定制合成服务的方式提供 MCE 抗衰老化合物库 Mini，我们为该库中的所有产品提供溶液包装或粉末包装。溶液包装中，370 个产品以 10 mM 浓度提供，10 个产品以 2 mM 浓度提供，1 个产品以 3 mg/mL 浓度提供。

溶液包装中，我们对于溶液状态稳定且溶解度不低于 10 mM 的产品，提供 10 mM 溶液；对于溶液状态稳定且溶解度介于 2~10 mM 的产品，我们提供 2 mM 溶液；对于溶液状态稳定、分子量不确定且溶解度不低于 3 mg/mL产品，我们提供 3 mg/mL 溶液。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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Compound Screening Libraries

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MCE 顾客使用化合物库产品发表的文献

  • 生物活性
  • 产品详情

活性描述 & 特点

Biological Activity

•   A unique collection of 381 bioactive anti-aging compounds for high throughput screening (HTS) and high content screening (HCS).

•   Targets include Sirtuin, mTOR, IGF-1R, AMPK, p53, Telomerase, Mitophagy, Mitochondrial Metabolism, COX, Cytochrome P450, Oxidase, etc.

•   A useful tool for anti-aging research.

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, medicinally active, and cell permeable.

•   Detailed compound information with structure, IC50, and brief introduction.

•   Validated NMR and HPLC to ensure high purity and quality.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 381 anti-aging compounds supplied as pre-dissolved Solutions or Solid
Solution: 370 compounds supplied in 10 mM solution, 10 compounds supplied in 2 mM solution, 1 compounds supplied in 3 mg/mL solution.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

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  •  形式（固体或溶液）
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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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产品名称：
Anti-Aging Compound Library Mini
目录号：
HY-L034M
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