•    A unique collection of 2,000,000 macrocycle compounds, generated by Macformer via Transformer architecture for automated macrocyclization of linear molecules from the ChEMBL database

•    Compounds in this library have Molecular Weight ranging from 450 to 900, and the number of main ring atoms ranging from 12 to 35 (the main ring is defined by the shortest path/minimum number of bonds).

•    All compounds can obtained by well-designed macrocyclization methods (RCM, click, ring expansion, macrolactonization/macroamidation, etc.). with success rate >70%.

•    Compounds passed MedChem selection filters to remove any inappropriate chemical structures and avoid false hits.