2. 一站式药筛
  3. 化合物库
  4. 乳酸化修饰化合物库
乳酸化修饰化合物库 - Lactylation Compound Library

Cat. No.: HY-L249

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乳酸化修饰作为近年来新兴的重要翻译后修饰形式，在连接细胞代谢重编程、表观遗传调控及信号转导网络中发挥关键作用。基于乳酸代谢—乳酸化修饰—下游信号通路的系统性研究框架，本文库系统覆盖包括组蛋白修饰调控酶（如 p300 及 HDACs）、糖酵解关键酶（如 PKM2、LDHA、GAPDH等）、转录调控因子（如 STAT3、HMGB1、p53）以及 HIF-1α、NF-κB、PI3K-AKT-mTOR 等经典信号通路节点在内的多层级靶点，能够全面反映乳酸化修饰在“代谢—表观遗传—信号”交互过程中的调控特征。

MCE 整合 0 个已知活性分子与潜在功能化合物，适用于多种研究场景，包括高通量药物筛选、抑制剂鉴定及作用机制解析。可用于系统评估乳酸化修饰在肿瘤代谢、免疫调控及炎症反应等生物过程中的功能作用，并高效筛选具有调控潜力的小分子候选物，从而为靶向代谢与表观遗传交叉通路的创新药物研发提供有力支持。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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  • 生物活性
  • 产品详情

活性描述 & 特点

Biological Activity

•   A unique collection of 0 lactylation-related compounds

•   Bioactivity and safety confirmed by preclinical research and clinical trials. Some have been approved by FDA.

•   Structurally diverse, bioactive, and cell permeable.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

•   All compounds are in stock and continuously updated.

产品详情

Product Details

Formulation:

A collection of 0 lactylation-related compounds supplied as pre-dissolved Solutions or Solid.

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    Lactylation Compound Library
    目录号：
    HY-L249
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