2. 一站式药筛
  3. 化合物库
  4. 生物活性化合物库系列
  5. 信号通路靶向化合物库
  6. TCA 循环代谢物库
TCA 循环代谢物库 - TCA Cycle Metabolite Compound Library

Cat. No.: HY-L231

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TCA 循环（三羧酸循环）-也称为克雷布斯循环或柠檬酸循环 (CAC)，是通过乙酰辅酶 A 的氧化，将碳水化合物、脂肪 和蛋白质中储存的能量释放出来的一系列化学反应。

几十年来，TCA循环一直被认为是细胞氧化磷酸化产生能量和生物合成的中心途径。研究表明，TCA 循环与多种疾病有关联，特别是癌症。结肠癌、肝癌等几种癌症中，出现了导致 TCA 循环代谢物产生失调的突变，表明 TCA 循环可能与癌症的发生有关。了解 TCA 循环在抑制或促进癌症进展中的作用和分子机制，将促进未来开发新的基于代谢物的癌症治疗方法。

MCE 可以提供 25 种 TCA 循环的中间产物，这些代谢物可用于 TCA 相关研究或代谢组学鉴定。

  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
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  • 生物活性
  • 产品详情
  • 化合物库组成

活性描述 & 特点

Biological Activity

•    A useful tool for TCA cycle related diseases drugs discovery.

•   Target diverse, medicinally active and cell permeable.

•   Bioactivity and safety confirmed by preclinical research and clinical trials.

•   More detailed compound information with structure, IC50, and other chemical & biological data.

•   High purity and quality validated by NMR and LC/MS.

产品详情

Product Details

Formulation:

A collection of 25 TCA cycle metabolite compounds supplied as pre-dissolved Solutions or Solid

Layout:

96-well storage tube or 96-well plate: 1st and 12th column are left empty.
384-well plate: the first two columns and the last two columns are left empty.
Compounds with different concentrations or dissolved in different solvents will be put on separate plates. This way of layout may increase the number of plates because there could be three solvents and three concentrations.
If you have other requirements, please let us know.

Container:

96- or 384-well Plate with Peelable Foil Seal; 96-well Format Sample Storage Tube With Screw Cap and Optional 2D Barcode

Storage:

-80°C

Shipping:

Blue ice or dry ice

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  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack
  • 96-well Plate with Peelable Foil Seal
  • 384-well Microplate with Peelable Foil Seal
  • 96-well Storage Tubes with Rack

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    产品名称：
    TCA Cycle Metabolite Compound Library
    目录号：
    HY-L231
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