2. Metabolic Enzyme/Protease NF-κB Immunology/Inflammation Apoptosis
  3. Mitochondrial Metabolism Reactive Oxygen Species (ROS) Apoptosis
  4. SDH-IN-36

SDH-IN-36 (Compound 17) 是一种 α-D-生育酚衍生物。SDH-IN-36 通过抑制 SDHC 和阻断电子传递，增加 ROS，诱导凋亡 (apoptosis)。SDH-IN-36 可以抑制多种肿瘤细胞的增殖，如 SSK4 (GI50 = 0.156 µM)、SSNU638 (GI50 = 0.659 µM) 和 SKATOIII (GI50 = 0.490 µM) 细胞。SDH-IN-36 可以显著抑制肿瘤生长。SDH-IN-36 可以用于癌症如胃癌的研究。

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SDH-IN-36

SDH-IN-36 Chemical Structure

CAS No. : 261929-60-6

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SDH-IN-36 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SDH-IN-36 (Compound 17) is a derivative of alpha-D-tocopherol. SDH-IN-36 increases ROS and induces apoptosis by inhibiting SDHC and blocking electron transfer. SDH-IN-36 can inhibit the proliferation of various tumor cells, such as SSK4 (GI50 = 0.156 µM), SSNU638 (GI50 = 0.659 µM), and SKATOIII (GI50 = 0.490 µM) cells. SDH-IN-36 can significantly inhibit tumor growth. SDH-IN-36 can be used for research on cancers such as gastric cancer[1].

分子量

487.76

Formula

C31H53NO3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SDH-IN-36 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SDH-IN-36261929-60-6Mitochondrial MetabolismReactive Oxygen Species (ROS)ApoptosisSDHCROSapoptosisSSK4SSNU638SKATOIIIgastric cancerInhibitorinhibitorinhibit

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目录号：
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