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B-Raf Proto-Oncogene

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By Targets:	Raf (1) Apoptosis (1) Bcl-2 Family (1) Caspase (1) COX (1) EGFR (1) FAK (1) Lipoxygenase (1)
By Research Areas:	Cancer (1)

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Targets Recommended: Raf

Cat. No.	Product Name	Target	Research Area	Chemical Structure

HY-181061

COX/5-LO-IN-2	COX EGFR Lipoxygenase FAK Raf Apoptosis Caspase Bcl-2 Family	Cancer
COX/5-LO-IN-2 是一种 COX2、EGFR、COX1、5-LOX、BRAF 和 FAK 抑制剂，其 IC₅₀ 值分别为 1.22 μM、2.5 μM、2.95 μM、4.65 μM、7.4 μM 和 12.2 μM。COX/5-LO-IN-2 可诱导细胞周期阻滞于 G2/M 期。COX/5-LO-IN-2 通过上调促凋亡蛋白 p53、Bax 和 caspase-7，以及下调抗凋亡蛋白 Bcl-2，从而触发凋亡 (apoptosis) 活性。COX/5-LO-IN-2 可用于乳腺癌研究。

Cat. No.	Compare	Product Name	Species	Source	图片

HY-P702921

	BRAF Protein, Human (Active, sf9, GST, His) BRaf1; RafB; Proto-Oncogene B-Raf; p94; v-Raf murine sarcoma viral Oncogene homolog B1	Human	Sf9 insect cells
	BRAF 蛋白 BRAF Protein, Human (Active, sf9, GST, His) 是重组的 BRAF 蛋白，由 Sf9 insect cells 表达。

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HY-P80794

	Phospho-BRAF (Thr401) Antibody (YA222) BRaf; BRaf1; RafB1; Serine/threonine-protein kinase B-Raf; Proto-Oncogene B-Raf; p94; v-Raf murine sarcoma viral Oncogene homolog B1	WB, IP	Human, Mouse, Rat
	Phospho-BRAF (Thr401) Antibody (YA222) 是一个兔来源、无偶联标记、抗磷酸化 BRAF (Thr401) 的 IgG 单克隆抗体。

HY-P85345

	BRAF Antibody (YA5037) BRaf; BRaf1; RafB1; Serine/threonine-protein kinase B-Raf; Proto-Oncogene B-Raf; p94; v-Raf murine sarcoma viral Oncogene homolog B1	WB; IHC-P; IHC-F; IF-Tissue; IP; FC; ICC/IF	Human, Mouse, Rat
	BRAF Antibody (YA5037) 是一个兔来源、无偶联标记、抗 BRAF 的单克隆抗体。

HY-P86220

	Phospho-BRAF(Thr401) Antibody (YA5912) BRaf; BRaf1; RafB1; Serine/threonine-protein kinase B-Raf; Proto-Oncogene B-Raf; p94; v-Raf murine sarcoma viral Oncogene homolog B1	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-BRAF(Thr401) Antibody (YA5912) 是一个兔来源、无偶联标记、抗磷酸化 BRAF(Thr401) 的 IgG 单克隆抗体。

HY-P85529

	BRAF Antibody (YA5221) FLJ95109; 94 kDa B Raf protein; B Raf 1; B Raf Proto Oncogene serine threonine protein kinase; B-Raf Proto-Oncogene serine/threonine-protein kinase; p94; BRaf 1; BRaf; BRaf_HUMAN; BRaf1; cRmil; MGC126806; MGC138284; Murine sarcoma viral; v-Raf; Oncogene homolog B1; Murine sarcoma viral v Raf Oncogene homolog B1; NS7; Oncogene BRaf1; p94; Proto-Oncogene B-Raf; Proto-Oncogene c-Rmil; RafB 1; RafB1; RMIL; Serine/threonine-protein kinase B-Raf; v Raf murine sarcoma viral Oncogene homolog B; v Raf murine sarcoma viral Oncogene homolog B1; v-Raf murine sarcoma viral Oncogene homolog B1	WB	Human, Mouse
	BRAF Antibody (YA5221) 是一个小鼠来源、无偶联标记、抗 BRAF 的单克隆抗体。

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BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

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