Search Result

Results for "

baseline

" in MCE Product Catalog:

By Targets:	Adrenergic Receptor (1) Akt (1) Drug Metabolite (1) LAG-3 (1) mAChR (1) Mitochondrial Metabolism (1) PROTACs (1) Ras (1)
By Research Areas:	Cancer (2) Endocrinology (1) Infection (1) Inflammation/Immunology (1) Neurological Disease (1)

抑制剂 & 激动剂

抗体抑制剂

没找到您心仪的产品？我们拥有更多针对信号通路的抑制剂、激动剂、调节剂

您还可以尝试以下方式，我们的专业人员为您服务

Cat. No.	Product Name	Target	Research Area	Chemical Structure

HY-13318A

Oseltamivir acid hydrochloride 70 篇以上引用文献 GS 4071 hydrochloride; Ro 64-0802 hydrochloride; Oseltamivir carboxylate hydrochloride	Drug Metabolite	Infection
奥斯他伟酸盐酸盐 Oseltamivir acid hydrochloride 是抗病毒剂 Oseltamivir (HY-13317) 酯的活性代谢产物。Oseltamivir acid hydrochloride 在毒性比分析中属于基线毒物。

HY-W046704

1-Methoxycyclopropanecarboxylic acid	Mitochondrial Metabolism	Others
1-Methoxycyclopropanecarboxylic acid 是一种解偶联剂，将呼吸作用刺激至基线水平的大约 160%。

HY-115376

Z62954982 ZINC08010136	Ras	Inflammation/Immunology
Z62954982 (ZINC08010136) 是一种强效的、选择性的、细胞渗透性强的 Rac1 (IC₅₀=12 μM) 抑制剂，比 NSC23766 (HY-15723A) (IC₅₀=50 μM) 有效性强 4 倍。Z62954982 干扰 Rac1/Tiam1 复合物，降低活性 Rac1 (GTP 结合的 Rac1) 的细胞质水平，而不影响其他 Rho GTPases (如，Cdc42 或 RhoA) 的活性。

HY-P99027

Ieramilimab LAG525; IMP701; Hu5A8	LAG-3	Cancer
埃拉利单抗 Ieramilimab (LAG525; IMP701) 是一种人源化 IgG4 单克隆抗体，结合 LAG-3，从而抑制 LAG-3 与 MHC-II 分子的相互作用。Ieramilimab 通过减少 T 细胞耗竭、增强细胞因子输出和细胞毒性，恢复 T 细胞和 NK 细胞介导的抗白血病免疫。Ieramilimab 增加细胞毒性 T 淋巴细胞的浸润，并降低调节性 T 细胞 (Tregs) 和表达 ADAM10 的肿瘤细胞的基线密度。Ieramilimab 可用于研究多种恶性肿瘤，包括黑色素瘤、肾细胞癌和晚期实体瘤。

HY-160469

INY-05-040	Akt PROTACs	Cancer
INY-05-040 是一种 AKT 降解剂，能够选择性地快速降解所有三种 AKT 亚型。INY-05-040 具有抗癌活性。INY-05-040 可抑制 288 种癌细胞系中的下游信号传导和细胞增殖。INY-05-040 可以抑制 AKT 信号传导并诱导应激丝裂原活化蛋白激酶 (MAPK) c-Jun 氨基端激酶 (JNK)。INY-05-040 对应激 MAPK 通路低基线激活的乳腺癌细胞系有效。INY-05-040 可用于抗癌研究。

HY-103204

RS100329 hydrochloride	Adrenergic Receptor	Endocrinology
RS100329 hydrochloride 是一种有效的选择性 α1A-肾上腺素能受体拮抗剂，拮抗 α1A、 α1D 和 α1B 的 pK_i 值分别为 9.6、7.9 和 7.5。RS100329 hydrochloride 对反射性尿道收缩有抑制作用。RS100329 hydrochloride 可用于良性前列腺增生的研究。

HY-114848

Amiprilose hydrochloride SM1213 hydrochloride; Therafectin hydrochloride	Others	Others
Amiprilose (SM1213) hydrochloride 是一种具有抗炎和免疫调节特性的新型合成碳水化合物，可使疼痛关节和肿胀关节数量、关节疼痛和肿胀指数、握力等指标恢复到基线水平。

HY-W754293

Deanol pidolate V0191; DMAE pidolate; DMAE PCA	mAChR	Neurological Disease
Deanol pidolate (V0191; DMAE pidolate) 是一种口服有效的促胆碱能剂，通过增加乙酰胆碱 (Ach) 释放来改善认知症状，且避免胆碱酯酶抑制剂的典型副作用。Deanol pidolate 能够缩短东莨菪碱对长期记忆的有害影响，并更快地恢复到基线水平。Deanol pidolate 可用于研究阿尔默茨病。

Cat. No.	Product Name	Target	Research Area	图片

HY-P99027

Ieramilimab LAG525; IMP701; Hu5A8	LAG-3	Cancer
埃拉利单抗 Ieramilimab (LAG525; IMP701) 是一种人源化 IgG4 单克隆抗体，结合 LAG-3，从而抑制 LAG-3 与 MHC-II 分子的相互作用。Ieramilimab 通过减少 T 细胞耗竭、增强细胞因子输出和细胞毒性，恢复 T 细胞和 NK 细胞介导的抗白血病免疫。Ieramilimab 增加细胞毒性 T 淋巴细胞的浸润，并降低调节性 T 细胞 (Tregs) 和表达 ADAM10 的肿瘤细胞的基线密度。Ieramilimab 可用于研究多种恶性肿瘤，包括黑色素瘤、肾细胞癌和晚期实体瘤。

Your information is safe with us. * Required Fields.

* 客户姓名：			* 公司或机构名称：
* Email：			* 联系电话：
* 产品名称：			* 需求量：
目录号：			CAS号：
留言给我们：

Bulk Inquiry

Inquiry Information

产品名称：
目录号：
需求量：

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature. Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred to a PVDF membrane and blocked with 5% non-fat milk in TBST for 2 hour at room temperature. The primary antibody (1/1000) and Loading control antibody (Beta Actin, HY-P80438, 1/10000) was used in 5% non-fat milk in TBST at 4°C overnight. Goat Anti-Mouse/Rabbit IgG-HRP Secondary Antibody (1/10000) was used for 1 hour at room temperature.

BODIPY 493/503 purchased from MedChemExpress. Usage Cited in: Nat Commun. 2025 Feb 1;16(1):1241. [Abstract]

MedchemExpress Validation 01

MedchemExpress Validation 03

Western blot analysis of extracts from THP-1(lane 2(20μg), Jurkat (lane 3(20μg) and NIH3T3(lane 4(20μg) using FOXO1A (HY-P80132) Rabbit mAb. Proteins were transferred

MedchemExpress Validation 04

MedchemExpress Validation

MedChemExpress (MCE) 只为有资质的科研机构、医药企业基于科学研究或药证申报的用途提供医药研发服务，不为任何个人或者非科研性质的、非用于药证申报使用等其他用途提供服务。	站点地图隐私声明
粤ICP备2021105330号-3 上海工商沪公网安备31011502019417 沪(浦)应急管危经许[2021]201709(QFYS) 营业执照（三证合一）
Copyright © 2013-2026 MedChemExpress. All Rights Reserved.

姓名
邮箱 *

Sorry, but the email address you supplied was invalid.

baseline

抑制剂 & 激动剂

抗体抑制剂

热门区域

A

B

C

F

G

H

J

L

N

Q

S

T

X

Y

Z