2. Neuronal Signaling
  3. Cholinesterase (ChE)
  4. SON38

SON38 是一种铜螯合剂，能螯合二价铜。SON38 能胆碱酯酶的活性，可以用于阿尔兹海默症的研究。

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SON38

SON38 Chemical Structure

CAS No. : 3034673-37-2

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SON38 相关抗体

Top Publications Citing Use of Products

查看 Cholinesterase (ChE) 亚型特异性产品:

查看所有亚型
AChE BChE

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

SON38 is a copper chelator capable of chelating divalent copper. SON38 can inhibit the activity of cholinesterases and has potential applications in Alzheimer's disease research[1].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
HepG2 IC50
> 100 μM
Compound: 12; SON38
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
[PMID: 35462163]
HepG2 IC50
> 100 μM
Compound: 12; SON38
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human HepG2 cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
[PMID: 35462163]
SH-SY5Y IC50
> 100 μM
Compound: 12; SON38
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 24 hrs by MTT assay
[PMID: 35462163]
SH-SY5Y IC50
> 100 μM
Compound: 12; SON38
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
Cytotoxicity against human SH-SY5Y cells assessed as inhibition of cell viability incubated for 48 hrs by MTT assay
[PMID: 35462163]
分子量

432.90

Formula

C21H25ClN4O4
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

SON38 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SON383034673-37-2SON 38SON-38Cholinesterase (ChE)Alzheimer’s diseaseInhibitorinhibitorinhibit

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目录号：
HY-159888
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