2. GPCR/G Protein
  3. GLP Receptor GCGR
  4. Survodutide sodium

Survodutide (BI 456906) sodium 是一种有效的、选择性的胰高血糖素受体/GLP-1 受体 (GCGR/GLP-1R) 双重激动剂，在 CHO-K1 细胞中的 EC50 值分别为 0.52 nM 和 0.33 nM。Survodutide sodium 是一种 29 个氨基酸的肽，是含有 C18 脂肪酸的有效酰化肽。Survodutide sodium 通过增加能量消耗和减少食物摄入来实现强大的抗肥胖功效。

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Custom Peptide Synthesis

Survodutide sodium

Survodutide sodium Chemical Structure

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1 mg ￥1300
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5 mg ￥2800
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10 mg ￥4200
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Customer Review

Other Forms of Survodutide sodium:

Survodutide sodium 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Survodutide (BI 456906) sodium is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively. Survodutide sodium, a 29-amino-acid peptide, is a potent acylated peptide containing a C18 fatty acid. Survodutide sodium has robust anti-obesity efficacy achieved by increasing energy expenditure and decreasing food intake[1].

体外研究
(In Vitro)

Survodutide (BI 456906) sodium 在内源性小鼠胰岛素瘤细胞系 MIN6 中 GLP-1R 的 EC50 为 0.36 nM，GLP-1 对其的 EC50 为 60 pM。在 0.5% 人和小鼠血浆中，Survodutide sodium 显示出与内源性 GLP-1 相似的效力。对于 GCGR，在 0.5% 人和小鼠血浆中，Survodutide sodium 的效力 (分别为 0.29 nM 和 0.17 nM) 比内源性胰高血糖素 (分别为 47 pM 和 30 pM) 低 6 倍[1]。
Survodutide sodium 的蛋白水解稳定性得益于 C 端酰胺化以及在 2 位引入非编码氨基酸 1-氨基环丁烷-1-羧酸 (Ac4c)，该位置已被确定为二肽基肽酶 4 的蛋白水解活性位点。通过在 24 位引入带有 C18 二酸的甘氨酸-丝氨酸接头，可以实现 Survodutide sodium 所需的延长终末半衰期[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Survodutide sodium 相关抗体:
体内研究
(In Vivo)

Survodutide (BI 456906；3、10、20、30 nmol/kg；皮下注射；每日；30 天) sodium 与最大有效剂量的索马鲁肽 (HY-114118；20、100 nmol/kg) 相比，对饮食诱导的肥胖小鼠具有更大的减肥功效。Survodutide sodium 剂量依赖性地降低血浆胰高血糖素[1]。
Survodutide (1、3、10、30、100 nmol/kg；皮下注射；单剂量) sodium 可剂量依赖性地减少 WT 小鼠的急性食物摄入量，但不会减少 GLP-1R KO 小鼠 (三周龄、雄性、瘦 NMRI 近交系小鼠)[1]。
Survodutide (1、3、10、30、100 nmol/kg；皮下注射；单剂量) sodium 单次给药后与体内胰高血糖素受体结合，增加肝脏烟酰胺 N-甲基转移酶 mRNA，并减少血浆丝氨酸和谷氨酰胺[1]。
Survodutide (皮下注射) sodium 在小鼠和狗中分别获得了 44 和 140 小时的平均停留时间以及 7 和 51 小时的 Tmax 值[1]。
Pharmacokinetic Parameters of Survodutide (BI 456906) in mice and dogs[1].

Mice (20 nmol/kg; SC) Dogs (10 nmol/kg; SC)
Tmax (h) 7 50.7
Cmax (nM) 84.9 62.0
AUC0-∞ (nM h) 4640 9540

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male C57BL6/J mice pre-fed with a 60% HFD (22 weeks)[1]
Dosage: 3, 10, 20, 30 nmol/kg
Administration: SC; daily; 30 days
Result: Dose-dependently reduced bodyweight from baseline by up to 32% at Day 28 at a dose of 30 nmol/kg.
分子量

4231.63 (free base)

Formula

C192H289N47O61·xNa
性状

固体

Sequence

His-{1-Aminocyclobutanecarboxylic acid}-Gln-Gly-Thr-Phe-Thr-Ser-Asp-Tyr-Ser-Lys-Tyr-Leu-Asp-Glu-Arg-Ala-Ala-Lys-Asp-Phe-Ile-{Lys(Gly-Ser-Gly-Ser-Gly-Gly-γGlu-C18 diacid)}-Trp-Leu-Glu-Ser-Ala-NH2
Sequence Shortening

H-{1-Aminocyclobutanecarboxylic acid}-QGTFTSDYSKYLDERAAKDFI-{Lys(GSGSGG-γGlu-C18 diacid)}-WLESA-NH2
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Sealed storage, away from moisture

Powder -80°C 2 years
-20°C 1 year

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

溶解性数据
细胞实验： 

H2O 中的溶解度 : 100 mg/mL (超声助溶)

  • 摩尔计算器

  • 稀释计算器

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量
=
浓度
×
体积
×
分子量 *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start)

C1

×
体积 (start)

V1

=
浓度 (final)

C2

×
体积 (final)

V2

动物溶解方案计算器
请输入动物实验的基本信息：

给药剂量

mg/kg

动物的平均体重

g

每只动物的给药体积

μL

动物数量

只
由于实验过程有损耗，建议您多配一只动物的量
计算结果
工作液所需浓度 : mg/mL
该产品水溶性佳，请具体参考实测 水 / PBS / Saline 中的溶解度数据。
您所需的储备液浓度超过该产品的实测溶解度，如有需要，请与 MCE 中国技术支持联系。
纯度 & 产品资料
参考文献

Survodutide sodium 相关分类

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

SurvodutideBI 456906BI456906BI-456906GLP ReceptorGCGRGlucagon Receptorglucagon receptorCHO-K1acylatedC18 fatty acidobesityenergy expenditurefood intakeInhibitorinhibitorinhibit

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t = $(drag).find("input"); var elemCancel = $(touch.target).closest(input).is(":focus"); if (elemCancel) { flag = false; } $("body,html").css({"user-select":"none"}); } function mouseUp(){ this.onmousemove=null; this.onmouseup=null; this.ontouchmove=null; this.ontouchend=null; if (drag.releaseCapture) { drag.releaseCapture(); } $("body,html").css({"user-select":"auto"}); } return false; } function dragMoves(drag) { drag.addEventListener("mousedown",function(ev){ downMove(drag, ev); }); drag.addEventListener("touchstart",function(ev){ downMove(drag, ev); }) } var dragGeneral = document.querySelector("#loginProGeneral"); var dragLogin = document.querySelector("#loginProLogin"); dragMoves(dragGeneral); dragMoves(dragLogin); }); // var initStopn = 0; // var targetTop = 537; // var targetTopDiv = 0; // var loginDivheight = 430; // isCnProdetail = true; // $('html,body').animate({scrollTop:0},1000); //$(".zhuce").offset().top; // function prodetailLogin() { // var stopn = $(window).scrollTop(); // var stopn2 = $(window).scrollTop() - initStopn; // var promise = $("#main_nav").offset().top; // var winheight= ($(window).height()); // var promisepro = 716; // // // // if (stopn >= promise) { // $('.pro_mask').css("top","88px"); // } // else { // $('.pro_mask').css("top","120px"); // } // // if (winheight < promisepro) { // if (stopn2 > 0) { // if (targetTop > 368) { // targetTop = targetTop - stopn2 <= 368 ? 368 : targetTop - stopn2; // } // } // } else { // if (stopn2 < 0) { // targetTop = targetTop - stopn2 >= 537 ? 537 : targetTop - stopn2; // } // loginDivheight = 430; // $('.pro_login').removeClass('divlogoverflow'); // } // // if (targetTop <= 368) { // let h1 = 650 - winheight; // let new_loginDivheight = h1 >= 0 ? 430 - h1 : 430 ; // $('.pro_login').height(new_loginDivheight); // let c_h = loginDivheight - new_loginDivheight; // targetTop = targetTop - c_h / 2; // loginDivheight = new_loginDivheight; // if (new_loginDivheight < 430) { // $('.pro_login').addClass('divlogoverflow'); // } else { // $('.pro_login').removeClass('divlogoverflow'); // } // // } // // $('.pro_login').css("top", targetTop + "px"); // initStopn = $(window).scrollTop(); // } var sel_array = $('[name="pro_cart_mg_num"]'); var mg_array = $('[name="pro_cart_mg"]'); var dw_sel_array = $('[name="pro_cart_dw_num"]'); var dw_array = $('[name="pro_cart_dw"]'); var eta_showStockType = "1"; var eta_infringementType = "0"; function updateProETA(){ var isChange = false; var isPrepare = false; var isETA = false; // var sel_num = $(currentE).val(); // if (parseInt(sh_stock_num) < parseInt(sel_num)) { // $('#pro_detail_eta').show(); // $('#pro_detail_eta').html(getEtaCnMessage()); // } else { // $('#pro_detail_eta').hide(); // $('#pro_detail_eta').html(""); // } var delivery = ''; dw_sel_array.each(function(index,domEle) { var option_dw = $(dw_array.eq(index)).val().split(";"); var dw_sh_stock_num = option_dw[6]; var dw_us_stock_num = option_dw[7]; var dw_select_num = $(domEle).val(); if (parseInt(dw_sh_stock_num) < parseInt(dw_select_num)) { isETA = true; if (dw_us_stock_num == 9527) { isChange = true; } if (dw_us_stock_num == 99999) { isPrepare = true; } delivery = $(domEle).closest('tr').find('.pro_price_3').text() return false; } }); //alert('isDW:'+isDW); sel_array.each(function(index,domEle){ var select_num = $(domEle).val(); var option_mg = $(mg_array.eq(index)).val().split(";"); var sh_stock_num = option_mg[6]; var us_stock_num = option_mg[7]; var eta_message = ''; if (parseInt(sh_stock_num) < parseInt(select_num)) { isETA = true; if (us_stock_num == 9527) { isChange = true; } if (us_stock_num == 99999) { isPrepare = true; } delivery = $(domEle).closest('tr').find('.pro_price_3').text() return false; } }); // 20200519 wdf if (isETA == true) { if (isPrepare || isChange) { $('#pro_detail_eta').html("预计 " + delivery + " 发货"); } else { var catNo = "HY-P4146B"; changeCnEtaMessage(isChange); //$('#pro_detail_eta').show(); $('#pro_detail_eta').html(getEtaCnMessage(catNo, isChange)); } } else { //$('#pro_detail_eta').hide(); $('#pro_detail_eta').html(""); } } function qtyChange(){ updateProETA(); } // Product Isoform by WDF 20180508 $(function () { fnSetIC50Style(); fnIsoformWidth(); proRelatedImgCN(); //normalSalineDisplacement(); }); // Isoform width function fnIsoformWidth(){ var isoformProList = $(".isoform-pro-list"); var isoformProListLen = isoformProList.length; for(var i = 0; i < isoformProListLen; i++){ var isoformProSpan = isoformProList.eq(i).find("span"); var isoformProSpanLen = isoformProSpan.length; if(isoformProSpanLen>4) { isoformProSpan.parent().css({"width":"100%"}); isoformProSpan.css({"width":"auto"}); } else { isoformProSpan.parent().css({"width":(isoformProSpanLen/4*100)+"%" }); isoformProSpan.css({"width":(1/isoformProSpanLen*100)+"%" }); } } } /* * Target&IC50 Table => 原理 * 1. 计算每个格子的宽度，如果格子的总宽度 <= iContainerW(固定行宽)，则一行显示; 否则多行显示 * 2. 多行的情况: 列数 = iContainerW/最宽单元格的列宽(取整); 列宽 = iContainerW/列数 * 3. 如果一行中, IC50值全是空，那么这一行 IC50 全隐藏，Isoform 垂直居中对齐 */ function fnSetIC50Style(){ var oContainer = $("#pro-ic50-tbl"); var iContainerW = 827; var spanLen = oContainer.find("span").length; var tdLen = spanLen/2; // 单元格总数 var spanArr = []; var spanTotalW = 0; var spanwMax = 0; // span 相加总长度 var lastW = 0; if(tdLen > 1){ for(var i = 0; i < tdLen; i++){ var spanW = [oContainer.find("td").eq(i).find("span").eq(0).outerWidth(),oContainer.find("td").eq(i).find("span").eq(1).outerWidth()].max(); spanArr.push(spanW); spanTotalW += spanW; if(i==tdLen-1){ lastW = oContainer.find("td").eq(i).find("span").eq(0).outerWidth(); } } } spanwMax = spanArr.max(); // console.log("spanwMax= " + spanwMax); // console.log("spanArr=" +spanArr); // 如果 spanwMax > iContainerW 分行; 否则, 一行显示 if(spanTotalW <= iContainerW){ oContainer.find("td").addClass("ic50-td0"); oContainer.find("td:last-child").css({"width": (iContainerW-lastW)+"px"}); // 最后一列宽度 oContainer.find(".ic50-td0").wrapAll(""); }else { var trtdNum = parseInt(iContainerW / spanwMax); // 每一行的列数 var tdWidth = iContainerW/trtdNum; //列宽 var trLen = spanLen/2/trtdNum; // 总行数 var lastTrNum = spanLen/2%trtdNum; //最后一行的个数 var lastColspan = trtdNum+1-lastTrNum; // 最后一行需要合并的单元格数 for (var j = 0; j < tdLen; j++) { for (var k = 0; k < trLen; k++) { if (parseInt(j / trtdNum) == k) { oContainer.find("td").eq(j).addClass("ic50-td" + k); } } } oContainer.find("td").css({"width": tdWidth + "px"}); // 设置列宽 oContainer.find("td:last-child").attr({"colspan": lastColspan}); //最后一行合并的单元格数量 oContainer.find("td:last-child").css({"width": lastColspan*tdWidth+"px"}); // 最后一列宽度 // tr 分组 for (var k = 0; k < trLen; k++) { oContainer.find(".ic50-td" + k).wrapAll(""); } } oContainer.find("td.ic50-td0 > p:first-child").css({"border-top":"0"}); // 第一行 p 的上border 是0 // 如果一行中 IC50 全是空，则这一行隐藏 var iTrLength = oContainer.find("tr>tr").length; var str = []; var tdLength = 0; console.log("tr="+iTrLength); for(var a = 0; a < iTrLength; a++){ tdLength = oContainer.find("tr>tr").eq(a).find("td").length; for(var b = 0; b < tdLength; b++ ){ var aa = oContainer.find("tr>tr").eq(a).find("td").eq(b).find("p").eq(1).text().replace(/\,|(^\s*)|(\s*$)/g, ""); str[a] += aa; } console.log("str[a]="+str[a]); if(str[a] == "undefined" || str[a] == "" || str[a] == null){ for(var b = 0; b < tdLength; b++ ){ oContainer.find("tr>tr").eq(a).find("td").eq(b).find("p").eq(1).css({"display":"none"}); oContainer.find("tr>tr").eq(a).find("td").eq(b).find("p").eq(0).css({"padding":"0"}); oContainer.find("tr>tr").eq(a).find("td").eq(b).find("p").eq(0).find("span").css({"padding":"8px 18px 6px"}); } } } } //最小值 Array.prototype.min = function() { var min = this[0]; var len = this.length; for (var i = 1; i < len; i++){ if (this[i] < min){ min = this[i]; } } return min; } //最大值 Array.prototype.max = function() { var max = this[0]; var len = this.length; for (var i = 1; i < len; i++){ if (this[i] > max) { max = this[i]; } } return max; } Number.prototype.toFloor = function (num) { return Math.floor(this * Math.pow(10, num)) / Math.pow(10, num); }; // end Product Isoform by WDF 20180203 //0){ return false; } else{ var count=$("#iqDetail_productCount").val().trim(); var amountUnit=$('#amountUnit option:selected').text(); $("#pro_num_p").html(count +" "+amountUnit); $(".form_submit_loading").show(); $(".btn_inquiry_submit").addClass("form_btn_submit_send") .removeClass("btn_inquiry_submit"); $("#btn_inquiry_submit").attr({"disabled":"disabled"}); $("#amountUnit").removeAttr("disabled"); $.ajax({ url:"mce_productDetail!inquiry.shtml", cache: false, data:$("#InquiryForm").serialize(), type:"POST", error: function(data) { $("#notice_titie").html("Uh-oh!"); $("#notice_content").html("It appears that we were unable to send an email to "+$("#cmInqriry_addrEmail1").val().trim()+". Please verify your email address and try again!"); $(".inquiry").hide(); $(".inquiry_success").css("margin-top","-"+$(".inquiry_success").outerHeight()/2+"px"); $(".inquiry_success").show(); $("#btn_inquiry_submit").removeAttr("disabled"); $(".form_submit_loading").hide(); $(".form_btn_submit_send").addClass("btn_inquiry_submit").removeClass("form_btn_submit_send"); }, success:function(data){ if(data==1){ $("#notice_titie").html("Congratulations! "); $("#notice_content").html(`We have received your inquiry regarding Survodutide sodium and will respond to you as soon as possible.`); $(".inquiry").hide(); $(".inquiry_success").css("margin-top","-"+$(".inquiry_success").outerHeight()/2+"px"); $(".inquiry_success").show(); $("#btn_inquiry_submit").removeAttr("disabled"); $(".form_submit_loading").hide(); $(".form_btn_submit_send").addClass("btn_inquiry_submit").removeClass("form_btn_submit_send"); $("#cmInqriry_lastName").val(""); $("#cmInqriry_companyName").val(""); $("#cmInqriry_addrEmail1").val(""); $("#cmInqriry_tel").val(""); $("#iqDetail_productCount").val(""); $("#cmInqriry_inquiryContent").val(""); }else{ $("#notice_titie").html("Uh-oh!"); $("#notice_content").html("It appears that we were unable to send an email to "+$("#cmInqriry_addrEmail1").val().trim()+". Please verify your email address and try again!"); $(".inquiry").hide(); $(".inquiry_success").css("margin-top","-"+$(".inquiry_success").outerHeight()/2+"px"); $(".inquiry_success").show(); $("#btn_inquiry_submit").removeAttr("disabled"); $(".form_submit_loading").hide(); $(".form_btn_submit_send").addClass("btn_inquiry_submit").removeClass("form_btn_submit_send"); } }, headers: {'X-Csrf-Token': csrfToken} }); } } var changerPdfVal = ''; var isShowPT = false; function checkShowPT() { isShowPT = true; if (changerPdfVal != '') { ChangerProductPdf(changerPdfVal); } } function ChangerProductPdf(value){ console.log(value); changerPdfVal = value; var catalogNo = "HY-P4146B"; var storeAt = "survodutide-sodium"; var pdf_array = new Array(); $.ajax({ url:'mce_productDetail!selectProductPdfById.shtml?mathdom='+Math.random(), cache:false, data:{'propdfId':value,'pro_catalogNo':catalogNo}, success:function(data){ if(data!=""){ //alert(data); window.eval(data); if(arrPdf.length>0){ var lot_no = $("#pdf_batch_no option:selected").val(); var lot_batch = $("#pdf_batch_no option:selected").text(); var pdf_coa = document.getElementById("productDetailBatch_pdf_coa"); var pdf_batch = document.getElementById("productDetailBatch_pdf_batch"); //alert(pdf_batch); //pdf_batch.innerHTML = ""; $(pdf_batch).html(""); var batch_txt = ""; var coa_txt = ""; for(var i=0;iCOA ("+arrPdf[i].objSize+" KB)"; }else if(arrPdf[i].objFile=="Elemental-Analysis-Report"){ coa_txt = coa_txt + "元素分析报告 ("+arrPdf[i].objSize+" KB)"; }else if(arrPdf[i].objFile=="HNMR"){ if (isShowPT) { coa_txt = coa_txt + "HNMR ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "HNMR ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-HNMR-link', arrPdf[i].objName, 'HNMR', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="CNMR"){ if (isShowPT) { coa_txt = coa_txt + "CNMR ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "CNMR ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-CNMR-link', arrPdf[i].objName, 'CNMR', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="RP-HPLC"){ if (isShowPT) { coa_txt = coa_txt + "RP-HPLC ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "RP-HPLC ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-RP-HPLC-link', arrPdf[i].objName, 'RP-HPLC', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="NP-HPLC"){ if (isShowPT) { coa_txt = coa_txt + "NP-HPLC ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "NP-HPLC ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-NP-HPLC-link', arrPdf[i].objName, 'NP-HPLC', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="MS"){ if (isShowPT) { coa_txt = coa_txt + "MS ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "MS ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-MS-link', arrPdf[i].objName, 'MS', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="LCMS"){ if (isShowPT) { coa_txt = coa_txt + "LCMS ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "LCMS ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-LCMS-link', arrPdf[i].objName, 'LCMS', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="IR"){ if (isShowPT) { coa_txt = coa_txt + "IR ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "IR ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-IR-link', arrPdf[i].objName, 'IR', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="GC"){ if (isShowPT) { coa_txt = coa_txt + "GC ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "GC ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-GC-link', arrPdf[i].objName, 'GC', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="OR"){ if (isShowPT) { coa_txt = coa_txt + "OR ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "OR ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-OR-link', arrPdf[i].objName, 'OR', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="SDS-PAGE"){ if (isShowPT) { coa_txt = coa_txt + "SDS-PAGE ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "SDS-PAGE ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-SDS-PAGE-link', arrPdf[i].objName, 'SDS-PAGE', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="Other Report"){ if (isShowPT) { coa_txt = coa_txt + "Other Report ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "Other Report ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-Other-Report-link', arrPdf[i].objName, 'Other Report', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="FNMR"){ if (isShowPT) { coa_txt = coa_txt + "FNMR ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "FNMR ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-FNMR-link', arrPdf[i].objName, 'FNMR', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="PNMR"){ if (isShowPT) { coa_txt = coa_txt + "PNMR ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "PNMR ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-PNMR-link', arrPdf[i].objName, 'PNMR', catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="NMR"){ if (isShowPT) { coa_txt = coa_txt + ""+arrPdf[i].objNmrType+" ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + ""+arrPdf[i].objNmrType+" ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-NMR-link', arrPdf[i].objName, arrPdf[i].objNmrType, catalogNo, lot_batch); pdf_array.push(pdf_obj); } }else if(arrPdf[i].objFile=="SEC-HPLC"){ if (isShowPT) { coa_txt = coa_txt + "SEC-HPLC ("+arrPdf[i].objSize+" KB)"; } else { coa_txt = coa_txt + "SEC-HPLC ("+arrPdf[i].objSize+" KB)"; var pdf_obj = new $.PdfObj('J-SEC-HPLC-link', arrPdf[i].objName, 'SEC-HPLC', catalogNo, lot_batch); pdf_array.push(pdf_obj); } } }else{ if(arrPdf[i].objFile=="Purity"){ batch_txt += "纯度： " + arrPdf[i].objName ; } else if (arrPdf[i].objFile=="Assay") { batch_txt += "含量： " + arrPdf[i].objName; } else{ batch_txt += "ee.: " + arrPdf[i].objName ; } } } //pdf_batch.innerHTML = batch_txt; //pdf_coa.innerHTML = coa_txt; $("#productDetailBatch_pdf_batch").html(batch_txt); $("#productDetailBatch_pdf_coa").html(coa_txt); } } if (pdf_array.length>0) { $.each(pdf_array, function(index, pdfobjTemp){ //console.log(pdfobjTemp.pdfname); $("#" + pdfobjTemp.pdfid).click(function () { pagePdfObj = pdfobjTemp; pagePdfObj.proName = `Survodutide sodium`; $("#J-HNMR-form .title").html("Request for " + pagePdfObj.pdftype + " Report"); $("#J-HNMR-form #lotNo").val(pagePdfObj.lotNo); modalOpen("#J-HNMR-form"); getUserBaseMessage(); }); }); } } }); } function Gettext(obj){ var txt=obj.options[obj.options.selectedIndex].text; return txt; } cart_sart(); //]]> function findClinicalsByCatalogNo(){ var catalogNo = "HY-P4146B"; $.ajax({ url:'mce_productDetail!findClinicalsByCatalogNo.shtml?mathdom='+Math.random(), type: 'post', cache:false, data:{'pro_catalogNo':catalogNo}, dataType: 'json', success:function(data){ var str_head = "" + "" + "NCT Number" + "Sponsor" + "Condition" + "Start Date" + "Phase" + "" + "" + ""; var str_foot = ""; var str_content = ""; $.each(data, function(i, item) { if (i==3) { //alert(i+","+item.phase); str_content += " "; } str_content += "" + item.nctNumber + ""; str_content += "" + item.sponsorCollaberators + ""; str_content += "
" + item.activeCondition + "
"; str_content += "" + item.startDate + ""; str_content += "" + item.phase + ""; }); $('#clinical_seo').html(str_head + str_content + str_foot); proClinicalStyle(); } }) } $("#datasheet_url").show(); $("#datasheet_footer_url").show(); $("#datasheet_span").show(); function checkUrl(c_url,type_id) { /*$.ajax({ url:'mce_productDetail!chenkUrlStatus.shtml?mathdom='+Math.random(), type: 'post', cache:false, data:{'curl':c_url}, dataType: 'json', success:function(data){ if (data.checkUrl == "success") { $("#" + type_id + "_url").show(); $("#" + type_id + "_footer_url").show(); $("#" + type_id + "_span").show(); } } })*/ $.ajax({ url: c_url, type: 'get', cache: false, dataType: 'jsonp', processData: false, complete: function(response) { if (response.status == 200) { $("#" + type_id + "_url").show(); $("#" + type_id + "_footer_url").show(); $("#" + type_id + "_span").show(); } }, error: function(data) {} }); } $(function(){ fnCPDRelated('#J-cpd-related-lib'); //fnCPDRelated('#J-cpd-related-mol'); //findRelatedProArray(); var pmsOutSessionId = $.cookie('pms-out-init'); console.log(pmsOutSessionId) //遮罩层屏蔽 if (pmsOutSessionId != "" && pmsOutSessionId !=null && pmsOutSessionId != undefined){ $("#loginProLogin").hide(); $("#loginProGeneral").hide(); $("#main").removeClass("gray-text");//遮罩层 $("#detail_price_pro").removeClass("is-disabled");//按钮控制 // // $("#loginProGeneral").hide(); // $("#loginProMask").removeClass("pro_mask"); } }); (function($, h, c) { var a = $([]), e = $.resize = $.extend($.resize, {}), i, k = "setTimeout", j = "resize", d = j + "-special-event", b = "delay", f = "throttleWindow"; e[b] = 350; e[f] = true; $.event.special[j] = { setup : function() { if (!e[f] && this[k]) { return false } var l = $(this); a = a.add(l); $.data(this, d, { w : l.width(), h : l.height() }); if (a.length === 1) { g() } }, teardown : function() { if (!e[f] && this[k]) { return false } var l = $(this); a = a.not(l); l.removeData(d); if (!a.length) { clearTimeout(i) } }, add : function(l) { if (!e[f] && this[k]) { return false } var n; function m(s, o, p) { var q = $(this), r = $.data(this, d); r.w = o !== c ? o : q.width(); r.h = p !== c ? p : q.height(); n.apply(this, arguments) } if ($.isFunction(l)) { n = l; return m } else { n = l.handler; l.handler = m } } }; function g() { i = h[k](function() { a.each(function() { var n = $(this), m = n.width(), l = n.height(), o = $ .data(this, d); if (m !== o.w || l !== o.h) { n.trigger(j, [ o.w = m, o.h = l ]) } }); g() }, e[b]) } })(jQuery, this); $('#loginProLogin').on('mousedown', function() { $('#loginProLogin').css('cursor','grab') }); $('#loginProLogin').on('mouseup', function() { $('#loginProLogin').css('cursor','move') }); $('#loginProGeneral').on('mousedown', function() { $('#loginProGeneral').css('cursor','grab') }); $('#loginProGeneral').on('mouseup', function() { $('#loginProGeneral').css('cursor','move') });