2. Membrane Transporter/Ion Channel Apoptosis
  3. Bcl-2 Family P-glycoprotein Apoptosis
  4. Tenacigenoside A

Tenacigenoside A 是一种选择性作用于 P-糖蛋白 (P-glycoprotein) 和凋亡相关蛋白 (BCL2、BCL-XL、BID) 的多药耐药逆转剂及凋亡 (apoptosis) 诱导剂。Tenacigenoside A 调节凋亡相关蛋白表达、抑制 P-gp 功能发挥关键活性，抑制肿瘤细胞增殖、诱导肿瘤细胞凋亡及逆转肿瘤多药耐药。Tenacigenoside A 可用于淋巴瘤等恶性肿瘤的研究。

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Tenacigenoside A

Tenacigenoside A Chemical Structure

CAS No. : 920502-42-7

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Tenacigenoside A 相关抗体

Top Publications Citing Use of Products

查看 Bcl-2 Family 亚型特异性产品:

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Bcl-2 Bcl-xL Bcl-W Mcl-1 Bfl-1 Bcl-B Bax Bak Bim BNIP3 Bad

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tenacigenoside A is a multidrug resistance reversal agent and apoptosis inducer that selectively acts on P-glycoprotein and apoptosis-related proteins (BCL2, BCL-XL, BID). Tenacigenoside A exerts its key activity by regulating the expression of apoptosis-related proteins and inhibiting P-gp function, thereby inhibiting tumor cell proliferation, inducing tumor cell apoptosis, and reversing multidrug resistance in tumors. Tenacigenoside A can be used in research on malignant tumors such as lymphoma[1].

体外研究
(In Vitro)

Tenacigenoside A 在 1、10、50 μL/mL 浓度下可诱导淋巴瘤细胞凋亡，20μg/mL 浓度下能逆转 P-gp 介导的多药耐药[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Tenacigenoside A 相关抗体:
分子量

668.81

Formula

C35H56O12
CAS 号
结构分类
初始来源
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tenacigenoside A 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tenacigenoside A920502-42-7Bcl-2 FamilyP-glycoproteinApoptosisP-gpPgpMultidrug resistance protein 1MDR1ATP-binding cassette sub-family B member 1ABCB1Cluster of differentiation 243CD243Inhibitorinhibitorinhibit

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