2. Cell Cycle/DNA Damage Apoptosis
  3. DNA/RNA Synthesis Nucleoside Antimetabolite/Analog Apoptosis
  4. Tezacitabine hydrate

Tezacitabine hydrate 是一种具有细胞生长抑制和细胞毒性的抗代谢剂，是一种核苷类似物 (nucleoside analogue)。Tezacitabine hydrate 不可逆地抑制核糖核苷酸还原酶 (ribonucleotide reductase) 并干扰 DNA 复制和修复。Tezacitabine hydrate 有效诱导细胞凋亡 (Apoptosis)，可用于白血病和实体瘤的研究。

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Tezacitabine hydrate

Tezacitabine hydrate Chemical Structure

CAS No. : 171176-43-5

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Tezacitabine hydrate 的其他形式现货产品:

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Other Forms of Tezacitabine hydrate:

Tezacitabine hydrate 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Tezacitabine hydrate is a cytostatic and cytotoxic antimetabolite and nucleoside analogue. Tezacitabine hydrate irreversibly inhibits the ribonucleotide reductase and interferes with DNA replication and repair. Tezacitabine hydrate effectively induces cells Apoptosis. Tezacitabine hydrate has the potential for leukemias and solid tumors (carcinomas) treatment[1][2].

IC50 & Target

Ribonucleotide reductase[1]
分子量

275.23

Formula

C10H14FN3O5
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Tezacitabine hydrate 相关分类

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  • 稀释计算器

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Tezacitabine171176-43-5DNA/RNA SynthesisNucleoside Antimetabolite/AnalogApoptosisCytostaticcytotoxicantimetaboliteCytidinefluorineribonucleotide reductaseDNAreplicationrepairantitumorInhibitorinhibitorinhibit

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产品名称：
Tezacitabine hydrate
目录号：
HY-106015
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