1. Anti-infection
  2. SARS-CoV
  3. TLP-3

TLP-3,一种 Temporin L (HY-P2523) 类似物,是一种 SARS-CoV-2 主蛋白酶 (Mpro) 抑制剂,其 IC50 为 7.0 μM。TLP-3 通过与关键酶残基形成稳定的氢键和疏水相互作用来抑制蛋白酶活性。TLP-3 可用于 SARS-CoV-2 感染的相关研究。

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Custom Peptide Synthesis

TLP-3

TLP-3 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TLP-3, Temporin L (HY-P2523) analogue, is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 7.0 μM. TLP-3 inhibits protease activity through stabilizing hydrogen bonding and hydrophobic interactions with key enzyme residues. TLP-3 can be used for the research of ARS-CoV‑2 infection[1].

体外研究
(In Vitro)

TLP-3 通过有利的结构域排布稳定 SARS-CoV-2 Mpro,并与 Mpro 的关键残基形成强氢键相互作用[1]
TLP-3 抑制 SARS-CoV-2 Mpro 活性,其 IC50 为 7.0 ± 1.5 μM[1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

1659.89

Formula

C83H110N20O17

Sequence

Ser-Ala-Phe-Trp-Gln-Trp-Phe-Ser-Lys-Phe-Leu-Gly-Arg

Sequence Shortening

SAFWQWFSKFLGR

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TLP-3
目录号:
HY-P11579
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