1. Antibody-drug Conjugate/ADC Related Immunology/Inflammation
  2. ADC Antibody CD22
  3. TRPH-222 Antibody

TRPH-222 Antibody  (Synonyms: CD22-4AP Antibody; CAT-02-106 Antibody)

目录号: HY-P991906
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技术支持

TRPH-222 Antibody (CD22-4AP Antibody) 是一种抗人 CD22 抗体,其每条重链上均有一个位点经过位点特异性修饰,表达甲酰甘氨酸 (FG),从而可以位点特异性地偶联美登素类有效载荷、蛋白酶不敏感间隔基以及用于与抗体 FG 残基上的醛基偶联的功能基团。TRPH-222 Antibody 可生成带有 ADC 有效载荷和连接子的抗体药物偶联物 (ADC) (TRPH-222)。TRPH-222 Antibody 可用于 NHL (非霍奇金淋巴瘤) 的研究。

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TRPH-222 Antibody

TRPH-222 Antibody Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

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  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

TRPH-222 Antibody (CD22-4AP Antibody) is an anti-human CD22 antibody site-specifically modified at one site per heavy chain to express formylglycine (FG), allowing site-specific conjugation of a maytansinoid payload, a protease-insensitive spacer, and a functional group for coupling to an aldehyde on antibody FG residues. TRPH-222 Antibody can generate antibody drug conjugate (ADC) (TRPH-222) with an ADC payload and a linker. TRPH-222 Antibody can be used for the study of NHL (non-Hodgkin's lymphoma)[1].

反应种属

Human

IC50 & Target

Siglec-2/CD22

基因 ID

933  [NCBI]

Accession
应用

ELISA, FACS, Functional assay

偶联物

Unconjugated

复溶方法

The product can be reconstituted/diluted with sterile PBS or saline.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
TRPH-222 Antibody
目录号:
HY-P991906
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