1. Anti-infection
  2. HIV
  3. U 88204

U 88204 是一种强效的 HIV-1 逆转录酶 (RT) 抑制剂,其 IC50 为 0.25 μM。U 88204 可抑制感染细胞中 HIV-1 的复制。U 88204 可用于 HIV 感染及艾滋病 (AIDs) 的研究 。

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U 88204

U 88204 Chemical Structure

CAS No. : 136816-76-7

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生物活性

U 88204 is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 of 0.25 μM. U 88204 blocks HIV-1 replication in infected cells. U 88204 can be used for the research on HIV-infection and of acquired immunodeficiency syndrome (AIDs)[1].

体外研究
(In Vitro)

U 88204 (compound 11) 在 MT-2/IIIb、PBMC/D34 和 H9/IIIb 细胞中强效抑制 HIV-1 复制,其 ED50 值分别为 0.3 μM、0.001 μM 和 0.04 μM,同时表现出低细胞毒性 (CC50 > 10 μM) [1]

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

分子量

363.47

Formula

C21H25N5O

CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
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The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
U 88204
目录号:
HY-180417
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