2. Anti-infection Metabolic Enzyme/Protease
  3. HIV HIV Protease
  4. U-96988

U-96988 (PNU-96988) 是一种非肽类 HIV-1 蛋白酶 (HIV-1 protease) 抑制剂，其 Ki 为 38 nM。U-96988 对 HIV-2 蛋白酶同样有效。U-96988 对 HIV-1IIIB 的 IC50 为 5 μM。U-96988 可用于研究 HIV 感染。

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U-96988

U-96988 Chemical Structure

CAS No. : 149394-65-0

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U-96988 相关抗体

Top Publications Citing Use of Products

查看 HIV 亚型特异性产品:

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HIV HIV-1 HIV-2

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

U-96988 (PNU-96988) is a non-peptide HIV-1 protease inhibitor with a Ki value of 38 nM. U-96988 is also effective against HIV-2 protease. U-96988 exhibits an IC50 for HIV-1IIIB of 5 μM. U-96988 can be used for research on HIV infection[1][2].

细胞效力
(Cellular Effect)
Cell Line Type Value Description References
H9 ED50
3 μM
Compound: 7
Tested for the antiviral activity against HIV-1 IIIB-infected H9 cells
Tested for the antiviral activity against HIV-1 IIIB-infected H9 cells
[PMID: 7932546]
MT4 ED50
3 μM
Compound: 7
Tested for the antiviral activity against HIV-1 IIIB-infected MT-4
Tested for the antiviral activity against HIV-1 IIIB-infected MT-4
[PMID: 7932546]
分子量

362.46

Formula

C24H26O3
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

U-96988 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

U-96988149394-65-0PNU-96988U96988U 96988PNU96988PNU 96988HIVHIV ProteaseHuman immunodeficiency virusprotein bindingfree drug concentrationperipheral blood mononuclear cells (PBMC)equilibrium distributionantiviral activityserum effectstructure-based designInhibitorinhibitorinhibit

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产品名称：
U-96988
目录号：
HY-19215
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