2. Anti-infection GPCR/G Protein Cell Cycle/DNA Damage
  3. Parasite Guanylate Cyclase Nucleoside Antimetabolite/Analog
  4. UA2239

UA2239 是一种抗疟剂，属于非环状核苷膦酸酯。UA2239 通过降低 cGMP 水平来破坏必需的 cGMP 依赖性出胞途径。UA2239 靶向鸟苷酸环化酶 α (guanylyl cyclase α)。UA2239 对疟原虫具有快速且不可逆的抑制作用。

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UA2239

UA2239 Chemical Structure

CAS No. : 2455422-89-4

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UA2239 相关抗体

Top Publications Citing Use of Products

查看 Parasite 亚型特异性产品:

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Amebae Coccidia Leishmania Mite Plasmodium Toxoplasma Trypanosoma Schistosome

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

UA2239 is an antimalarial agent and acyclic nucleoside phosphonate. UA2239 disrupts the essential cGMP-dependent egress pathway by decreasing cGMP levels. UA2239 targets guanylyl cyclase α. UA2239 demonstrates rapid and irreversible inhibitory effects on Plasmodium parasites[1].

IC50 & Target[1]

Plasmodium

 

分子量

347.18

Formula

C9H12N5Na2O5P
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

UA2239 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

UA22392455422-89-4UA 2239UA-2239ParasiteGuanylate CyclaseNucleoside Antimetabolite/AnalogInhibitorinhibitorinhibit

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