1. GPCR/G Protein
  2. GLP Receptor GCGR
  3. UTG-4

UTG-4 是一种 GLP-1RGIPRGCGR 激动剂,EC50 分别为 126.3 pM,29.2 pM,250.2 pM。UTG-4 与 HSA 结合 (Kd = 14.6 μM)。UTG-4 能有效缓解内皮-间质转化。UTG-4 能促进体重减轻、抑制食物摄入、改善葡萄糖耐量,并具有显著的抗动脉粥样硬化作用。

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Custom Peptide Synthesis

UTG-4

UTG-4 Chemical Structure

1.  客户无需承担相应的运输费用。

2.  同一机构(单位)同一产品试用装仅限申领一次,同一机构(单位)一年内

     可免费申领三个不同产品的试用装。

3.  试用装只面向终端客户

规格 是否有货
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100 mg   询价  
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Customer Review

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

UTG-4 is a GLP-1R, GIPR, and GCGR agonist with EC50 values of 126.3 pM, 29.2 pM, and 250.2 pM, respectively. UTG-4 binds to HSA (Kd = 14.6 μM). UTG-4 effectively alleviates endothelial-mesenchymal transition. UTG-4 promotes weight loss, inhibits food intake, improves glucose tolerance, and has a significant anti-atherosclerotic effect[1].

IC50 & Target

EC50: 126.3 pM, 29.2 pM, and 250.2 pM for GLP-1R, GIPR, and GCGR, respectively[1]

分子量

4920.52

Formula

C230H349N49O70

运输条件

Room temperature in continental US; may vary elsewhere.

储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.

纯度 & 产品资料
参考文献
  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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产品名称:
UTG-4
目录号:
HY-P11487
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