2. Immunology/Inflammation NF-κB Metabolic Enzyme/Protease
  3. Reactive Oxygen Species (ROS)
  4. Z226407860

Z226407860 是一种 RING-盒蛋白 1 (RBX1) 抑制剂。Z226407860 通过抑制 RBX1 减轻屋尘螨诱导的气道上皮损伤及 ROS 蓄积。Z226407860 可用于哮喘的研究。

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Z226407860

Z226407860 Chemical Structure

CAS No. : 2419496-02-7

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Z226407860 相关抗体

Top Publications Citing Use of Products

  • 生物活性

  • 纯度 & 产品资料

  • 参考文献

生物活性

Z226407860 is a RING-box protein 1 (RBX1) inhibitor. Z226407860 reduces house dust mite-induced airway epithelial injury and ROS accumulation by inhibiting RBX1. Z226407860 can be used for the research of asthma[1].

体外研究
(In Vitro)

Z226407860 (5 μM) 可强效抑制正常 HBE 细胞中 RBX1 mRNA 和蛋白的表达，抑制屋尘螨 (HDM) 诱导的 HBE 细胞中 RBX1 蛋白过表达[1]。
Z226407860 (5 μM) 可通过恢复闭合蛋白 (Occludin) 和上皮钙黏蛋白 (E-cadherin) 的水平，缓解 HDM 诱导的 HBE 上皮屏障功能障碍，减轻细胞中活性氧 (ROS) 的累积[1]。

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Z226407860 相关抗体:
分子量

540.67

Formula

C28H36N4O5S
CAS 号
运输条件

Room temperature in continental US; may vary elsewhere.
储存方式

Please store the product under the recommended conditions in the Certificate of Analysis.
纯度 & 产品资料
参考文献

Z226407860 相关分类

  • 摩尔计算器

  • 稀释计算器

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

质量   浓度   体积   分子量 *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

浓度 (start) × 体积 (start) = 浓度 (final) × 体积 (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Z2264078602419496-02-7Z 226407860Z-226407860Reactive Oxygen Species (ROS)RBX1 InhibitorasthmaHBE cellsInhibitorinhibitorinhibit

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