Rhodium-catalyzed hydroarylation and hydroalkenylation of alkynes using organo [2-(hydroxymethyl) phenyl] dimethylsilanes

Y Nakao, M Takeda, J Chen, T Hiyama

文献索引：Nakao, Yoshiaki; Takeda, Masahide; Chen, Jinshui; Hiyama, Tamejiro Synlett, 2008 , # 5 p. 774 - 776

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被引用次数: 10

摘要

We first examined the reaction of [2-(hydroxymethyl)phenyl]phenyldimethylsilane (1a: 1.5 mmol) with 4-octyne (2a: 1.0 mmol) in the presence of [Rh(OH)(cod)] 2 (3.0 mol% Rh) in toluene at 100 °C using various bisphosphine ligands [1a] and found that 1,2-bis(diphenylphosphino) benzene (DPPBz) was effective to afford (E)-4-phenyl-4-octene (3aa) in 59% yield (Table [1] , entry 1). [6] Other rhodium complexes such as [RhCl(cod)] 2 and [RhCl(ethylene) 2 ] 2 ...