A short efficient route to acronycine and other acridones

S Horne, R Rodrigo

文献索引：Horne, Stephen; Rodrigo, Russell Journal of the Chemical Society, Chemical Communications, 1991 , # 15 p. 1046 - 1048

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被引用次数: 3

摘要

Acronycine 1, a tetracyclic antitumour acridone alkaloid132 is a well-known example of this group of natural products3 isolated from species of plants belonging to the Rutaceae family. Acridones are always synthesized from benzenoid starting materials either by Ullman reaction to form the diphenylamine, followed by Friedel-Crafts cyclization2.4 or by what is commonly regarded as a 'biomimetic' route where the benzoylation to produce a benzophenone precedes an ...