Reduction of Δ 2-isoxazolines-2. A facile synthesis of 3 (2H)-furanones.

DP Curran, DH Singleton

文献索引：Curran, Dennis P.; Singleton, David H. Tetrahedron Letters, 1983 , vol. 24, # 20 p. 2079 - 2082

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被引用次数: 35

摘要

Abstract. A simple synthesis of the 3 (2H)-furanone ring system is described. The 3 (2H)- furanone moeity is a central structural unit in a growing number of natural products including simple compounds such as bullatenone and geiparvarin and more complex compounds such as jatrophone, the eremantholides, and lychnophorolide. 2 Many of these 3 (2H)- furanone natural products possess significant tumor-inhibiting properties. Previous ...