Synthesis of phenolic natural products using palladium catalyzed coupling reactions

RW Bates, CJ Gabel, J Ji, T Rama-Devi

文献索引：Bates, Roderick W.; Gabel, Christine J.; Ji, Jianhua; Rama-Devi, Thota Tetrahedron, 1995 , vol. 51, # 30 p. 8199 - 8212

全文：HTML全文

被引用次数: 53

摘要

Derivatives of 2, 4-diiodophenol are shown to undergo palladium catalyzed carbonylation and alkyne coupling reactions in excellent to moderate yield and high regioselectivity. The scope of these reactions is explored. Palladium catalyzed reactions are employed as the key steps in the synthesis of three phenolic natural products: Plicatin B, Drupanin and Eutypine.