A rapid, chromatography-free route to substituted acridine–isoalloxazine conjugates under microwave irradiation

…, LLE Crouch, S Grieve, HL Maloney, GR Peczkowski…

文献索引：Johns, Stephen C.; Crouch, Laurie L.E.; Grieve, Stephen; Maloney, Holly L.; Peczkowski, Gary R.; Jones, Allison E.; Sharp, Duncan; Smith, Robert B. Tetrahedron Letters, 2014 , vol. 55, # 22 p. 3308 - 3311

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被引用次数: 3

摘要

Abstract Microwave irradiation was applied to a sequence of condensation reactions from readily available 9-chloroacridines to provide a range of novel acridine–isoalloxazine conjugates. The combination of these two moieties, both of biological interest, was achieved by a chromatography-free route.