A convenient method for the aromatic amino-Claisen rearrangement of N-(1, 1-disubstituted-allyl) anilines

…, MA Lucas, JM Taylor, AD Ward, NM Williamson

文献索引：Cooper; Lucas; Taylor; Ward; Williamson Synthesis, 2001 , # 4 p. 621 - 625

被引用次数: 26

摘要

Abstract: N-(1, 1-Disubstituted-allyl) anilines are rearranged cleanly and in high yield to 2-(3, 3-disubstituted-allyl) anilines using a catalytic amount of p-toluenesulfonic acid in acetonitrile/water (10: 1). Key words: amino-Claisen, rearrangement, aromatic amines, alkenes, alkynes

7471-09-2

(1,1-二甲基-2-丙炔)-苯胺

~55%

~80%

Achieving control over the branched/linear selectivity in pa...

[Dubovyk, Igor; Watson, Iain D. G.; Yudin, Andrei K. Journal of Organic Chemistry, 2013 , vol. 78, # 4 p. 1559 - 1575]

Synthesis of α, α-Disubstituted Aryl Amines by Rhodium-Catal...

[Arnold, Jeffrey S.; Cizio, Gregory T.; Nguyen, Hien M. Organic Letters, 2011 , vol. 13, # 20 p. 5576 - 5579]

A new synthesis of secondary allylic aliphatic and aromatic ...

[Spaltenstein, Andreas; Carpino, Philip A.; Hopkins, Paul B. Tetrahedron Letters, 1986 , vol. 27, # 2 p. 147 - 150]

Synthesis of α, α-Disubstituted Aryl Amines by Rhodium-Catal...

[Arnold, Jeffrey S.; Cizio, Gregory T.; Nguyen, Hien M. Organic Letters, 2011 , vol. 13, # 20 p. 5576 - 5579]