Facile deallylation protocols for the preparation of N-unsubstituted triazoles and tetrazoles

…, Z Huo, T Jin, C Kanazawa, Y Yamamoto

文献索引：Kamijo, Shin; Huo, Zhibao; Jin, Tienan; Kanazawa, Chikashi; Yamamoto, Yoshinori Journal of Organic Chemistry, 2005 , vol. 70, # 16 p. 6389 - 6397

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被引用次数: 26

摘要

Two facile deallylation protocols have been developed for the preparation of N- unsubstituted triazoles and tetrazoles. The first protocol is a direct deallylation using a combination of a catalytic amount of nickel complex, NiCl2 (dppe), and a stoichiometric amount of Grignard reagent, t BuMgCl. The second protocol is a stepwise deallylation through consecutive reactions of isomerization and ozonolysis. The isomerization from N- ...