Synthetic communications

Synthesis of Quinolines by N-Deformylation and Aromatization via Solvent-Free, High-Speed Ball Milling

J Yu, Z Li, W Su

文献索引：Yu, Jingbo; Li, Zhenhua; Su, Weike Synthetic Communications, 2013 , vol. 43, # 3 p. 361 - 374,14

被引用次数: 6

摘要

Quinoline skeletons are effective pharmacophores in medicinal chemistry that possess a broad spectrum of biological activities [ 1 1. (a) Kleeman , A. ; Engel , J. ; Kutscher , B. ; Reichert , D. Pharmaceutical Substances, Synthesis, Patents, Applications ; Thieme : Stuttgart , 2001 ; (b)

~30%

~95%

~10%

~98%

~98%

… deformylation of N??formyldihydroquinolines employing ferr...

[Kumar, Kalvi Hemanth; Perumal, Paramasivan T. Journal of Heterocyclic Chemistry, 2008 , vol. 45, # 2 p. 597 - 599]

Regioselective Reactions of Organozinc Reagents with 2, 4-Di...

[Shiota, Takeshi; Yamamori, Teruo Journal of Organic Chemistry, 1999 , vol. 64, # 2 p. 453 - 457]

Synthesis and structure-activity relationships of 9-substitu...

[Cheng; Lee; Klutchko; Winters; Reynolds; Welch; Flynn; Doherty Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 24 p. 2999 - 3002]