Palladium (0)??Catalyzed Alkynyl and Allenyl Iminium Ion Cyclizations Leading to 1, 4??Disubstituted 1, 2, 3, 6??Tetrahydropyridines

H Tsukamoto, Y Kondo

文献索引：Tsukamoto, Hirokazu; Kondo, Yoshinori Angewandte Chemie - International Edition, 2008 , vol. 47, # 26 p. 4851 - 4854

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被引用次数: 25

摘要

Piperidines, aliphatic six-membered nitrogen-containing heterocycles, are among the most promising therapeutic agents for a wide variety of diseases, including Alzheimer s disease and Parkinson s disease.[1] The development of new and efficient methods for the preparation of structurally diverse piperidine derivatives is desired for the drug-discovery process.[2] The introduction of a variety of substituent groups into preformed piperidine ...