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举例 :可输入Filippa Pettersson 或者 Cancer Res. 75(6) , 1102-12, (2015) 或者10.1002/anie.201600521

Tetrahedron

An efficient synthesis of 1α, 25-dihydroxy vitamin D 3

L Vanmaele, PJ De Clercq, M Vandewalle

文献索引:Tetrahedron, , vol. 41, # 1 p. 141 - 144

全文:HTML全文

被引用次数: 29

摘要

Terrakhv~ Vol. ... mmol), imidazole (295 mg; 4.35 mmol) and $e&-bu- tyldimethylsilyl chloride (367 mg; 2.44 mmol) in DMF (20 mL) is stirred under argon at 25OC for 5 h. After addition of an equal volume of hexane ... LJ Vanmaele, PJ De Clercq and M. Vandewalle, Tetrahedron Lett ...

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Pre-骨化三醇PTAD加合物结构式

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Pre-骨化三醇PTAD加合物

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骨化三醇结构式

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1,25-dihydroxy-previtamin D(3)结构式

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(4aR,6aR,7R,9aR,11S)-11-((S)-5-hydroxy-2-methylcyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione结构式

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(4aR,6aR,7R,9aR,11S)-11-((R)-5-hydroxy-2-methyl-3-oxocyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione结构式

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骨化三醇结构式

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(4aR,6aR,7R,9aR,11S)-11-((S)-5-((tert-butyldimethylsilyl)oxy)-2-methylcyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione结构式

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骨化三醇结构式

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(4aR,6aR,7R,9aR,11S)-11-((R)-5-((tert-butyldimethylsilyl)oxy)-2-methyl-3-oxocyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione结构式

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骨化三醇结构式

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Pre-骨化三醇PTAD加合物结构式

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Pre-骨化三醇PTAD加合物

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骨化三醇结构式

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4-苯基脲唑结构式

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Pre-骨化三醇PTAD加合物结构式

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25-hydroxy previtamin D3结构式

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Pre-骨化三醇PTAD加合物结构式

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Pre-骨化三醇PTAD加合物

(4aR,6aR,7R,9aR,11S)-11-((S)-5-hydroxy-2-methylcyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione结构式

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Pre-骨化三醇PTAD加合物结构式

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Pre-骨化三醇PTAD加合物

(4aR,6aR,7R,9aR,11S)-11-((S)-5-((tert-butyldimethylsilyl)oxy)-2-methylcyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione结构式

86307-42-8

(4aR,6aR,7R,9aR...

~%

Pre-骨化三醇PTAD加合物结构式

86307-44-0

Pre-骨化三醇PTAD加合物

(4aR,6aR,7R,9aR,11S)-11-((R)-5-((tert-butyldimethylsilyl)oxy)-2-methyl-3-oxocyclohex-1-en-1-yl)-7-((R)-6-hydroxy-6-methylheptan-2-yl)-6a-methyl-2-phenyl-4a,6,6a,7,8,9,9a,11-octahydro-1H,5H-cyclopenta[f][1,2,4]triazolo[1,2-a]cinnoline-1,3(2H)-dione结构式

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(4aR,6aR,7R,9aR...

~%

Pre-骨化三醇PTAD加合物结构式

86307-44-0

Pre-骨化三醇PTAD加合物

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