Efficient and clean synthesis of N-alkyl carbamates by transcarboxylation and O-alkylation coupled reactions using a DBU–CO 2 zwitterionic carbamic complex in …

…, MO da Silva, VC Costa, UP Rodrigues-Filho…

文献索引：Perez, Eduardo R; Da Silva, Michele Odnicki; Costa, Vanessa C; Rodrigues-Filho, Ubirajara P; Franco, Douglas W Tetrahedron Letters, 2002 , vol. 43, # 22 p. 4091 - 4093

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被引用次数: 93

摘要

N-Alkyl carbamates were obtained with good to excellent yields by clean and mild transcarboxylation of several amines with the previously synthesized DBU–CO2 complex and subsequent O-alkylation. Transcarboxylation was found to be selective, as only carbamate was formed from 1-hydroxy-2-aminobutanol.