Syntheses of some 2??hydroxypyrazine 1??oxides

…, S Masano, M Tsutsui, F Yamamoto…

文献索引：Ohta, Akihiro; Masano, Sawako; Tsutsui, Mayumi; Yamamoto, Fusako; Suzuki, Sumie; et al. Journal of Heterocyclic Chemistry, 1981 , vol. 18, p. 555 - 558

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被引用次数: 8

摘要

Abstract A series of 2-hydroxypyrazine 1-oxides were prepared from the corresponding chloropyrazines by two methods, including oxidation processes in satisfactory yields. The treatment of 2, 3-diphenylpyrazine 1, 4-dioxide (6) led to 2, 3-dichloro-5, 6-diphenylpyrazine (7) and 2-chloro-5, 6-diphenylpyrazine 1-oxide (8), and the latter was converted to 5, 6- diphenyl-2-hydroxypyrazine 1-oxide (9) by an alkaline hydrolysis.