Preparation of enantiopure 2, 2, 5, 5-tetramethyl-3, 4-hexanediol and its use in catalytic enantioselective oxidation of sulfides to sulfoxides

Y Yamanoi, T Imamoto

文献索引：Yamanoi, Yoshinori; Imamoto, Tsuneo Journal of Organic Chemistry, 1997 , vol. 62, # 24 p. 8560 - 8564

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被引用次数: 91

摘要

Optically active 1, 2-diols and related substrates play significant roles as chiral auxiliaries in the synthesis of natural products and biologically active compounds. 1 Recently, chiral catalysts derived from certain C2-symmetric 1, 2-diol ligands have been found to show high enantioselectivities in some asymmetric reactions. 2 These successful results led us to design a more effective chiral ligand. We considered that 2, 2, 5, 5-tetramethyl-3, 4- ...