To study the chemical constituents from the ethyl acetate extracts of Cremastra appendiculata.The compounds from the ethyl acetate extracts were isolated by the silica gel column and Sephadex LH-20 column chromatography, their structures were elucidated by the spectral analysis and chemical evidence.Seven componds were separated and identified as fumaric acid (1), dimethylhexyl phthalate (2), L-pyroglutamic acid (3), 2-furoic acid (4), vanillic acid (5), p-coumaric acid (6), protocatechuic acid (7).Compounds 1 to 6 are obtained from this plant for the first time.