The first regioselective metalation and functionalization of unprotected 4-halobenzoic acids

F Gohier, AS Castanet, J Mortier

文献索引：Journal of Organic Chemistry, , vol. 70, # 4 p. 1501 - 1504

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被引用次数: 33

摘要

... The Journal of Organic ... J. Org. Chem. ... These results suggest the formation of 3Li-1a and 3Li,5Li-1a as intermediates (Scheme 2). Unlike aliphatic dimetalation which has been used extensively in organic synthesis, 19 dimetalation of aromatic compounds has remained relatively ...