An amino alcohol ligand for highly enantioselective addition of organozinc reagents to aldehydes: serendipity rules

WA Nugent

文献索引：Organic Letters, , vol. 4, # 13 p. 2133 - 2136

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被引用次数: 69

摘要

... Volume: Page: ... Organic Letters. ... a All reactions contained aldehyde (3.0 mmol), Et 2 Zn (6.0 mmol), amino alcohol (1R,2S)-4 (0.15 mmol), and tert-butylbenzene as internal standard (300 μL) in 2:1 hexane−toluene (9 mL) at room temperature for 3 h except as ...