First synthesis, characterization, and evidence for the presence of hydroxycinnamic acid sulfate and glucuronide conjugates in human biological fluids as a result of …

R Fumeaux, C Menozzi-Smarrito, A Stalmach…

文献索引：Fumeaux, Rene; Menozzi-Smarrito, Candice; Stalmach, Angelique; Munari, Caroline; Kraehenbuehl, Karin; Steiling, Heike; Crozier, Alan; Williamson, Gary; Barron, Denis Organic and Biomolecular Chemistry, 2010 , vol. 8, # 22 p. 5199 - 5211

全文：HTML全文

被引用次数: 33

摘要

A systematic investigation of the human metabolism of hydroxycinnamic acid conjugates was carried out. A set of 24 potential human metabolites of coffee polyphenols has been chemically prepared, and used as analytical standards for unequivocal identifications. These included glucuronide conjugates and sulfate esters of caffeic, ferulic, isoferulic, m- coumaric and p-coumaric acids as well as their dihydro derivatives. A particular focus has ...